Evidence map›Paper›PMID 25371798›Full record

ArticleJundishapur journal of microbiology2014

Isolation, Characterization and Selection of Avermectin-Producing Streptomyces avermitilis Strains From Soil Samples.

Samia Siddique, Quratulain Syed, Ahmad Adnan, Fahim Ashraf Qureshi

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Article in Jundishapur journal of microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

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11citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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  3. Production and Extraction of Red Bioactive Pigment fromIndian journal of microbiology · 2025
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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Samia SiddiqueDepartment of Chemistry, Government College University, Lahore, Pakistan.
Quratulain SyedFood and Biotechnology Research Center, Pakistan Council of Scientific and Industrial Research Laboratories Complex Ferozepur, Lahore, Pakistan.
Ahmad AdnanDepartment of Chemistry, Government College University, Lahore, Pakistan.
Fahim Ashraf QureshiOffice of Research, Innovation and Commercialization, Comsats Institute of Information and Technology, Islamabad, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStreptomyces avermitilis, belonging to Actinomycetes, is specialized for production of avermectin, used as an anthelmintic and insecticidal agent. It is mostly found in soil and its isolation is very crucial for medically important avermectin production.

objectivesIn the present study, 10 bacterial isolates lacking antimicrobial activities were isolated from the soil samples collected from different areas of Lahore, Pakistan. MATERIALS AND

methodsThree distinctive localities of Lahore were opted for soil assortment to isolate S. avermitilis. About 50 isolates of Streptomyces species were attained through selective prescreening procedures. All of these isolates were studied for production of the secondary metabolite, avermectin. Different test like soluble pigment color and melanin formation were used for identification. Biochemical characterizations of those isolates closely resembling the control in morphological characteristics, soluble pigment color and melanin formation tests were performed.

resultsThe 10 selected isolates were identified as the avermectin-producing strain by fermentation and characterized on ISP2 medium for aerial and reverse side mycelia color, soluble pigment color and melanin formation, in comparison with S. avermitilis DSM 41445. The best avermectin-producing isolate S1-C (10.15 mg/L) showed similar result as S. avermitilis DSM 41445, when subjected for culture characteristics analysis in different media along with biochemical characterization.

conclusionsFrom the results, it was concluded that agricultural lands around Pakistan Council of Scientific and Industrial Research (PCSIR) Campus Lahore were rich sources of industrially important Streptomyces, especially S. avermitilis.

Indexed as

Anti-Infective AgentsAvermectinStreptomyces

Identifiers

PMID25371798
PMCPMC4217667

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