Evidence map›Paper›PMID 25371725›Full record

ArticleExperimental and therapeutic medicine2014

Red yeast rice repairs kidney damage and reduces inflammatory transcription factors in rat models of hyperlipidemia.

Mei Ding, Daoyuan Si, Wenqi Zhang, Zhaohui Feng, Min He, Ping Yang

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Mei DingDepartment of Cardiology, China-Japan Union Hospital of Jilin University, Changchun, Jilin 130033, P.R. China.
Daoyuan SiDepartment of Cardiology, China-Japan Union Hospital of Jilin University, Changchun, Jilin 130033, P.R. China.
Wenqi ZhangDepartment of Cardiology, China-Japan Union Hospital of Jilin University, Changchun, Jilin 130033, P.R. China.
Zhaohui FengDepartment of Cardiology, China-Japan Union Hospital of Jilin University, Changchun, Jilin 130033, P.R. China.
Min HeDepartment of Cardiology, China-Japan Union Hospital of Jilin University, Changchun, Jilin 130033, P.R. China.
Ping YangDepartment of Cardiology, China-Japan Union Hospital of Jilin University, Changchun, Jilin 130033, P.R. China.
Jilin University · CNUnion Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Xuezhikang (XZK), an extract of red yeast rice, has been widely used for the management of hyperlipidemia and coronary heart disease (CHD); however, the effects of XZK treatment on kidney injury have not yet been fully identified. The aim of the current study was to evaluate the effects of XZK on the kidneys and investigate the related mechanisms in a rat model of hyperlipidemia. Thus, the effect on inflammatory transcription factors and kidney damage was investigated with

Indexed as

hyperlipidimiainterleukin-6kidney functiontumor necrosis factor-αxuezhikang

Identifiers

PMID25371725
PMCPMC4217782
OpenAlexW2050072954

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.