ArticleExperimental and therapeutic medicine2014
microRNAs as novel biomarkers of schizophrenia (Review).
Article in Experimental and therapeutic medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Peripheral Blood-Based Gene Expression Studies in Schizophrenia: A Systematic Review.Frontiers in genetics · 2021Pooled it
- MicroRNAs as biomarkers and molecular mediators of cognitive dysfunction in schizophrenia.Journal of neural transmission (Vienna, Austria : 1996) · 2026Review
- Analysis of Normalizers and Neurodevelopment-Related microRNAs in the Prefrontal Cortex and in the Sperm of SHR Rats.International journal of molecular sciences · 2025Article
- An In Vitro Study for the Role of Schizophrenia-Related Potential miRNAs in the Regulation of COMT Gene.Molecular neurobiology · 2024Article
- Translational bioinformatics and data science for biomarker discovery in mental health: an analytical review.Briefings in bioinformatics · 2024Review
- Disclosing common biological signatures and predicting new therapeutic targets in schizophrenia and obsessive-compulsive disorder by integrated bioinformatics analysis.BMC psychiatry · 2023Article
- The Long-Term Effects of Early Life Stress on the Modulation of miR-19 Levels.Frontiers in psychiatry · 2020Article
- miRNA-Coordinated Schizophrenia Risk Network Cross-Talk With Cardiovascular Repair and Opposed Gliomagenesis.Frontiers in genetics · 2020Article
- The Relationship between Gene Polymorphism of miRNAs Regulating FGA and Schizophrenia.Open access Macedonian journal of medical sciences · 2019Article
- A comprehensive review of the genetic and biological evidence supports a role for MicroRNA-137 in the etiology of schizophrenia.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2018Review
- MiRNAs of peripheral blood as the biomarker of schizophrenia.Hereditas · 2018Review
- Chronically dysregulated NOTCH1 interactome in the dentate gyrus after traumatic brain injury.PloS one · 2017Article
- Genomic Editing of Non-Coding RNA Genes with CRISPR/Cas9 Ushers in a Potential Novel Approach to Study and Treat Schizophrenia.Frontiers in molecular neuroscience · 2017Review
- miRNAs and their role in the correlation between schizophrenia and cancer (Review).Molecular medicine reports · 2016Review
- MicroRNAs 29b and 181a down-regulate the expression of the norepinephrine transporter and glucocorticoid receptors in PC12 cells.Journal of neurochemistry · 2016Article
- Biomarkers in schizophrenia: A focus on blood based diagnostics and theranostics.World journal of psychiatry · 2016Review
- A role for miR-19 in the migration of adult-born neurons and schizophrenia.Neurogenesis (Austin, Tex.) · 2016Article
- Association between single nucleotide polymorphisms in MiR219-1 and MiR137 and susceptibility to schizophrenia in a Chinese population.FEBS open bio · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Schizophrenia is a severe mental illness and the most common complex neuropsychiatric disorder. To date, the etiology of schizophrenia is unclear; consequently, the diagnosis of schizophrenia is controversial. Biomarkers that reflect the dysregulations observed in schizophrenia may potentially assist the diagnosis of the disorder. However, the majority of these biomarkers are found in the brain tissue, which is not readily accessible, leading to the search for novel biomarkers that are present in the peripheral blood. microRNAs (miRNAs) are small non-coding RNAs that function as post-transcriptional regulators of gene expression. Previous investigations have revealed that miRNAs may play a potential role in neurodevelopment and maturation, including neurite outgrowth, dendritogenesis and dendritic spine formation. These developments highlight the significance of miRNAs as potential diagnostic biomarkers for schizophrenia. To date, miRNA biomarkers have been predominantly extracted from the brain tissue; however, future studies should examine the use of peripheral blood miRNAs as biomarkers, as these are more accessible.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.