Evidence map›Paper›PMID 25371584›Full record

ArticleAfrican journal of traditional, complementary, and alternative medicines : AJTCAM2014

Estimating the yin-yang nature of Western herbs: a potential tool based on antioxidation-oxidation theory.

Marilena Gilca, Laura Gaman, Daniela Lixandru, Irina Stoian

Open access · diamondAbstract read
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Article in African journal of traditional, complementary, and alternative medicines : AJTCAM, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Marilena GilcaBiochemistry Dept., Faculty of General Medicine, "Carol Davila" University of Medicine and Pharmacy, B-dul " Eroilor Sanitari" nr.8, sector 6, code 76241, Bucharest, Romania.
Laura GamanBiochemistry Dept., Faculty of General Medicine, "Carol Davila" University of Medicine and Pharmacy, B-dul " Eroilor Sanitari" nr.8, sector 6, code 76241, Bucharest, Romania.
Daniela LixandruBiochemistry Dept., Faculty of General Medicine, "Carol Davila" University of Medicine and Pharmacy, B-dul " Eroilor Sanitari" nr.8, sector 6, code 76241, Bucharest, Romania.
Irina StoianBiochemistry Dept., Faculty of General Medicine, "Carol Davila" University of Medicine and Pharmacy, B-dul " Eroilor Sanitari" nr.8, sector 6, code 76241, Bucharest, Romania ; R&D IRIST LABMED SRL, Str. Miraslau, nr. 24, sector 3, code 031235, Bucharest, Romania.
Carol Davila University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOne of the biggest obstacles to progress in traditional Chinese medicine (TCM) development in Western countries is the difficulty of applying the traditional concepts to the Western medicinal plants, which are not traditionally described in ancient literature. During recent years, new advances in the field of understanding Yin/Yang aspects from a modern bioscientific point of view have led to the conclusion that antioxidationoxidation concepts might mirror a Yin-Yang relationship.

methodsThis study was intended to integrate the Yin-Yang theory of the traditional Chinese medicine with modern antioxidation-oxidation theory, and to propose a biochemical tool based on redox parameters (e.g. antioxidant capacity, chemiluminescence-CL signal inducing capacity), usable for the classification of Western medicinal plants from Yin/Yang perspective. Trolox equivalent antioxidant capacity (TEAC) of six vegetal aqueous extracts (Symphitum officinalae (radix)-SYM, Inula helenium (radix)-INU, Calendula officinalis (flores)-CAL, Angelica arhanghelica (folium)ANG(F), Angelica arhanghelica (radix)-ANG(R), Ecbalium Elaterium (fruits)-ECB) and luminol-enhanced chemiluminescence of PMNL on addition of these vegetal extracts were measured. Percentages from the maximal or minimal values obtained were calculated for each extract (TEAC%, PMNL stimulation%, PMNL inhibition%, relative speed of action% (RSA%%)), specific Yin-Yang significance was assigned to each relative parameter. In the end, an integration of all the relative values was done, in order to find a global "Yin" or a "Yang" trait of each vegetal extract.

resultsTEAC decreased in the following order: SYM > INU > CAL >ANG(F) > ANG(R > ECB. Three vegetal extracts (SYM > INU > ECB) decreased the luminol-enhanced chemiluminescence of PMNL, two (ANG(R) > ANG(F)) increased it, while one (CAL) had a dual effect. After the integration of the percentages, CAL was found to have a global "Yang" trait, while the rest of the plants had a global "Yin" trait.

conclusionsTEAC% and PMNL inhibition% appears to correlate with the Yin properties of herbs, while PMNL stimulation% and RSA% might correlate with Yang aspects within the formal TCM classification system, and may be useful criteria in describing the Western herbs from a TCM point of view.

Indexed as

AntioxidantsMedicine, Chinese TraditionalPlant ExtractsPlants, MedicinalYin-YangAntioxidantsPlant ExtractsantioxidantchemiluminescenceherbsTCMTEACYangYin

Identifiers

PMID25371584
PMCPMC4202440
OpenAlexW2028005807

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.