ArticleJournal of experimental botany2015
Deep sequencing reveals important roles of microRNAs in response to drought and salinity stress in cotton.
Article in Journal of experimental botany, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 120 papers, 1 of them a synthesis that pooled it.
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Who cites it
120 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The role of microRNAs in responses to drought and heat stress in peanut (Arachis hypogaea).The plant genome · 2023Pooled it
- Characterization, evolution, and expression profiling of cotton DUF677 protein family and their potential role in drought and salt stress response.BMC plant biology · 2026Article
- The multifaceted regulatory network of microRNA396: Orchestrating plant plasticity through coordinating development and various stresses.Journal of integrative plant biology · 2026Review
- Identification and Expression Analysis of the Potato (Plants (Basel, Switzerland) · 2026Article
- The Gibberellin 2-Oxidase GeneInternational journal of molecular sciences · 2026Article
- Limitations of Single Prediction Tools in miRNA Profiling of Grapevine Viral Coinfection.Genes · 2026Article
- Non-coding RNAs in plant stress responses: molecular insights and agricultural applications.Plant biotechnology journal · 2025Review
- Overexpression of Lol-miR11467 negatively affects osmotic resistance in Larix kaempferi 3 × L. gmelinii 9.BMC plant biology · 2025Article
- DRB1 and DRB2 Are Required for an Appropriate miRNA-Mediated Molecular Response to Salt Stress inPlants (Basel, Switzerland) · 2025Article
- A review on strategies for crop improvement against drought stress through molecular insights.3 Biotech · 2024Review
- Predicting abiotic stress-responsive miRNA in plants based on multi-source features fusion and graph neural network.Plant methods · 2024Article
- Genetic and Epigenetic Responses of Autochthonous Grapevine Cultivars from the 'Epirus' Region of Greece upon Consecutive Drought Stress.Plants (Basel, Switzerland) · 2023Article
- Genome-wide analysis of the LAZ1 gene family in Gossypium hirsutum.Molecular biology reports · 2023Article
- Foliar Application of Melatonin Positively Affects the Physio-Biochemical Characteristics of Cotton (Plants (Basel, Switzerland) · 2023Article
- Advances in understanding epigenetic regulation of plant trichome development: a comprehensive review.Horticulture research · 2023Article
- Bottom-Up Effects of Drought-Stressed Cotton Plants on Performance and Feeding Behavior ofPlants (Basel, Switzerland) · 2023Article
- Roles of S-Adenosylmethionine and Its Derivatives in Salt Tolerance of Cotton.International journal of molecular sciences · 2023Review
- Zn Supplementation Mitigates Drought Effects on Cotton by Improving Photosynthetic Performance and Antioxidant Defense Mechanisms.Antioxidants (Basel, Switzerland) · 2023Article
- ASmiR: a machine learning framework for prediction of abiotic stress-specific miRNAs in plants.Functional & integrative genomics · 2023Article
- Genome-Wide Identification and Evolutionary Analysis ofPlants (Basel, Switzerland) · 2023Article
60 more citing papers are in PubMed but not listed here.
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Authors and funding
4 authors.
Funding
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Abstract
Drought and salinity are two major environmental factors adversely affecting plant growth and productivity. However, the regulatory mechanism is unknown. In this study, the potential roles of small regulatory microRNAs (miRNAs) in cotton response to those stresses were investigated. Using next-generation deep sequencing, a total of 337 miRNAs with precursors were identified, comprising 289 known miRNAs and 48 novel miRNAs. Of these miRNAs, 155 miRNAs were expressed differentially. Target prediction, Gene Ontology (GO)-based functional classification, and Kyoto Encyclopedia of Genes and Genomes (KEGG)-based functional enrichment show that these miRNAs might play roles in response to salinity and drought stresses through targeting a series of stress-related genes. Degradome sequencing analysis showed that at least 55 predicted target genes were further validated to be regulated by 60 miRNAs. CitationRank-based literature mining was employed to determinhe the importance of genes related to drought and salinity stress. The NAC, MYB, and MAPK families were ranked top under the context of drought and salinity, indicating their important roles for the plant to combat drought and salinity stress. According to target prediction, a series of cotton miRNAs are associated with these top-ranked genes, including miR164, miR172, miR396, miR1520, miR6158, ghr-n24, ghr-n56, and ghr-n59. Interestingly, 163 cotton miRNAs were also identified to target 210 genes that are important in fibre development. These results will contribute to cotton stress-resistant breeding as well as understanding fibre development.
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