Evidence map›Paper›PMID 25371270›Full record

ReviewLife (Basel, Switzerland)2012

Molecular mechanisms of survival strategies in extreme conditions.

Salvatore Magazù, Federica Migliardo, Miguel A Gonzalez, Claudia Mondelli, Stewart F Parker, Beata G Vertessy

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

Salvatore MagazùDepartment of Physics, University of Messina, Viale D'Alcontres 31, P.O. Box 55-98166, Messina, Italy. smagazu@unime.it.
Federica MigliardoDepartment of Physics, University of Messina, Viale D'Alcontres 31, P.O. Box 55-98166, Messina, Italy. fmigliardo@unime.it.
Miguel A GonzalezInstitut Laue Langevin, 6, Rue Jules Horowitz, F-38042 Grenoble Cedex 9, France. gonzalez@ill.fr.
Claudia MondelliCNR-IOM-OGG, Institut Laue Langevin, 6, Rue Jules Horowitz, F-38042 Grenoble Cedex 9, France. mondelli@ill.fr.
Stewart F ParkerISIS Facility, Rutherford Appleton Laboratory, Chilton, Oxon, OX11 0QX, UK. stewart.parker@stfc.ac.uk.
Beata G VertessyInstitute of Enzymology, Research Center for Natural Sciences, Hungarian Academy of Science, Budapest, Hungary. vertessy@enzim.hu.
Institut Laue-Langevin · FRUniversity of Messina · ITBudapest University of Technology and Economics · HURutherford Appleton Laboratory · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Today, one of the major challenges in biophysics is to disclose the molecular mechanisms underlying biological processes. In such a frame, the understanding of the survival strategies in extreme conditions received a lot of attention both from the scientific and applicative points of view. Since nature provides precious suggestions to be applied for improving the quality of life, extremophiles are considered as useful model-systems. The main goal of this review is to present an overview of some systems, with a particular emphasis on trehalose playing a key role in several extremophile organisms. The attention is focused on the relation among the structural and dynamic properties of biomolecules and bioprotective mechanisms, as investigated by complementary spectroscopic techniques at low- and high-temperature values.

Identifiers

PMID25371270
PMCPMC4187154
OpenAlexW2124023554

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.