ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2016
Is vitamin D insufficiency or deficiency related to the development of osteochondritis dissecans?
Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Osteochondritis Dissecans of the Knee: Etiology and Pathogenetic Mechanisms. A Systematic Review.Cartilage · 2020Pooled it
- Quantifying Risk Factors for Osteochondritis Dissecans in Children: A Propensity-Matched Retrospective Cohort Study.Orthopaedic journal of sports medicine · 2026Article
- Juvenile Osteochondritis Dissecans: A Case Report.Diagnostics (Basel, Switzerland) · 2024Article
- The importance of bone health for pediatric athletes: From juvenile osteochondritis dissecans to relative energy deficiency in sports.Journal of the Pediatric Orthopaedic Society of North America · 2024Article
- Osteochondritis dissecans of the knee: Epidemiology, etiology, and natural history.Journal of children's orthopaedics · 2023Review
- Gel-Based Autologous Chondrocyte Implantation in a Patient with Noncontained Osteochondral Knee Defect at 9-Year Follow-Up.Case reports in orthopedics · 2022Article
- Osteochondral Lesions of the Talus: A Review on Talus Osteochondral Injuries, Including Osteochondritis Dissecans.Cartilage · 2021Review
- Osteochondritis Dissecans Lesion of the Trochlear Groove: A Case of Nonsurgical Management for a Rare Lesion.Case reports in orthopedics · 2021Article
- Juvenile osteochondritis dissecans (JOCD) of the knee: current concepts review.EFORT open reviews · 2019Review
- Direct comparison of different surgical approaches in a woman with bilateral osteochondrosis dissecans of her knees: a case report.Journal of medical case reports · 2016Article
- Knee osteochondritis dissecans-treatment technical aspects.Journal of orthopaedicsArticle
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aetiology of osteochondritis dissecans is still unclear. The aim of this prospective pilot study was to analyse whether vitamin D insufficiency, or deficiency, might be a contributing etiological factor in the development of an OCD lesion.
methodsThe serum level of vitamin D3 in 23 consecutive patients (12 male and 11 female) suffering from a stage III, or stages III and IV, OCD lesion (mostly stage III) admitted for surgery was measured.
resultsThe patients' mean age was 31.3 years and most of them already exhibited closed epiphyseal plates. In the majority of patients (18/23), a distinct vitamin D3 deficiency was found, two patients were vitamin D3-insufficient and, in three patients, the vitamin D3 level reached the lowest normal value.
conclusionThese first data show that a vitamin D3 deficiency rather than an insufficiency may be involved in the development of OCD lesions. Probably, with a vitamin D3 substitution, the development of an advanced OCD stage could be avoided. Further analyses, including morphological analyses regarding a possible osteomalacia, and examination of the PTH and other determinants of the bone metabolism, should be undertaken to either confirm or refute these data. LEVEL OF EVIDENCE: IV.
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