Evidence map›Paper›PMID 25370821›Full record

ArticleThe Journal of organic chemistry2014

Photoassisted diversity-oriented synthesis: accessing 2,6-epoxyazocane (oxamorphan) cores.

Olga A Mukhina, N N Bhuvan Kumar, Teresa M Cowger, Andrei G Kutateladze

Abstract read
In one paragraph

Article in The Journal of organic chemistry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Photoassisted access to complex polyheterocycles containing a β-lactam moiety.Journal of photochemistry and photobiology. A, Chemistry · 2016
    Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Olga A MukhinaDepartment of Chemistry and Biochemistry, University of Denver , Denver, Colorado 80208, United States.
N N Bhuvan Kumar
Teresa M Cowger
Andrei G Kutateladze

Funding

Topologically Unique Scaffolds in Photoassisted Diversity Oriented Synthesis (PDOR15GM093930 · NIGMS · UNIVERSITY OF DENVER (COLORADO SEMINARY) · PI KUTATELADZE, ANDREI G · 2010 to 2017
$1.1M
NIGMS NIH HHS GM093930NIGMS NIH HHS R15 GM093930
6 · The paper itself

Abstract

The modular synthesis of photoprecursors and their photoinduced cyclization into substituted 1-benzazocanes of two distinct topologies is described. The key step producing an extended polyheterocyclic system involves the photogeneration of azaxylylenes and their subsequent intramolecular cycloaddition with furan-containing pendants tethered either via the aniline nitrogen or through the carbonyl group containing arm. The primary photoproducts-secondary or tertiary anilines which are not acylated at the nitrogen atom-undergo facile acid-catalyzed or spontaneous ring-opening-ring-closing rearrangement to yield fused polyheterocyclic structures possessing a 2,6-epoxyazocane (or oxamorphan) core.

Indexed as

Cycloaddition ReactionCycloheptanesHeterocyclic CompoundsMolecular StructurePhotochemical ProcessesStereoisomerism2,6-epoxyazocaneCycloheptanesHeterocyclic Compounds

Identifiers

PMID25370821
PMCPMC4242042

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.