Evidence map›Paper›PMID 25370453›Full record

ReviewPharmacogenetics and genomics2015

PharmGKB summary: very important pharmacogene information for CYP4F2.

Maria L Alvarellos, Katrin Sangkuhl, Roxana Daneshjou, Michelle Whirl-Carrillo, Russ B Altman, Teri E Klein

Abstract readReview
In one paragraph

Review in Pharmacogenetics and genomics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Observational
  3. Review
  4. PharmVar GeneFocus: CYP4F2.Clinical pharmacology and therapeutics · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Role of Genetic Variations in the Hepatic Handling of Drugs.International journal of molecular sciences · 2020 · on this map
    Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maria L AlvarellosDepartments of aGenetics bBioengineering, Stanford University, Stanford, California, USA.
Katrin Sangkuhl
Roxana Daneshjou
Michelle Whirl-Carrillo
Russ B Altman
Teri E Klein

Funding

INSTITUTIONAL TRAINING GRANT IN GENOME SCIENCET32HG000044 · NHGRI · STANFORD UNIVERSITY · PI MICHAEL P. SNYDER · 1995 to 2026
$32.2M
PharmGKB: pharmacogenomics knowledge for precision medicineR24GM061374 · NIGMS · STANFORD UNIVERSITY · PI ALTMAN, RUSS BIAGIO, KLEIN, TERI ELLEN · 2010 to 2018
$25.2M
GENETICS TRAINING PROGRAM FOR PHD CANDIDATEST32GM007790 · NIGMS · STANFORD UNIVERSITY · PI BRUNET, ANNE, KINGSLEY, DAVID M · 1985 to 2020
$12.8M
NHGRI NIH HHS T32 HG000044NIGMS NIH HHS R24 GM061374PHS HHS NIH/NIGMS R24 GM61374
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

PharmacogeneticsCytochrome P-450 Enzyme SystemCytochrome P450 Family 4HumansHydroxyeicosatetraenoic AcidsLeukotriene B4Warfarin20-hydroxy-5,8,11,14-eicosatetraenoic acidCYP4F2 protein, humanCytochrome P-450 Enzyme SystemCytochrome P450 Family 4Hydroxyeicosatetraenoic AcidsLeukotriene B4Warfarin

Identifiers

PMID25370453
PMCPMC4261059

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.