Evidence map›Paper›PMID 25370134›Full record

ReviewThe Clinical journal of pain2015

The Medicinal Cannabis Treatment Agreement: Providing Information to Chronic Pain Patients Through a Written Document.

Barth Wilsey, J Hampton Atkinson, Thomas D Marcotte, Igor Grant

Registry-linked trialAbstract readReview
In one paragraph

Review in The Clinical journal of pain, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02460692 (A Randomized Controlled Trial of Dronabinol and Vaporized Cannabis in Chronic Low Back Pain), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02460692 phase2completednot on this mapstarted 2016, after this paper: background citation

A Randomized Controlled Trial of Dronabinol and Vaporized Cannabis in Chronic Low Back Pain

TypeinterventionalSponsorUniversity of California, San DiegoRan2016 to 2020Enrolled131ConditionsCannabis, Low Back Pain, Neuropathic PainArmsPlacebos, dronabinol, Vaporized Cannabis 3.7% THC/5.6% CBD
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Barth Wilsey*Department of Physical Medicine & Rehabilitation, VA Northern California Health Care System †Department of Physical Medicine and Rehabilitation, University of California Davis Medical Center, Sacramento ‡VA San Diego Health Care System §Department of Psychiatry, University of California, San Diego, La Jolla, CA.
J Hampton Atkinson
Thomas D Marcotte
Igor Grant

Funding

The Effect of Vaporized Cannabis on Neuropathic Pain in Spinal Cord InjuryR01DA030424 · NIDA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI ZHAO, HOLLY · 2011 to 2014
$895k
NIDA NIH HHS R01 DA030424NIDA NIH HHS R01DA030424
6 · The paper itself

Abstract

aimPain practitioners would seem to have an obligation to understand and inform their patients on key issues of the evidence base on cannabinoid therapeutics. One way to fulfill this obligation might be to borrow from concepts developed in the prescription of opioids: the use of a written agreement to describe and minimize risks. Regrettably, the widespread adoption of opioids was undertaken while harmful effects were minimized; obviously, no one wants to repeat this misstep.

objectiveThis article describes a method of educating patients in a manner analogous to other treatment agreements.

backgroundSurveys have demonstrated that pain is the most common indication for medical use of cannabis. As more individuals gain access to this botanical product through state ballot initiatives and legislative mandate, the pain specialist is likely to be confronted by patients either seeking such treatment where permitted, or otherwise inquiring about its potential benefits and harms, and alternative pharmaceuticals containing cannabinoids.

methodsPubMed searches were conducted using the following keywords: cannabis guidelines, harmful effects of cannabis, medical marijuana, medicinal cannabis, opioid cannabis interaction, cannabis dependence and cannabis abuse

results: The authors selected individual tenets a medicinal cannabis patient would be asked to review and acknowledge via signature.

conclusionsUndoubtedly, the knowledge base concerning risks will be an iterative process as we learn more about the long-term use of medicinal cannabis. But we should start the process now so that patients may be instructed about our current conception of what the use of medicinal cannabis entails.

Indexed as

ConsensusPatient Education as TopicChronic PainFemaleHumansMaleMedical MarijuanaMedical Marijuana

Identifiers

PMID25370134
PMCPMC4417655

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.