Evidence map›Paper›PMID 25369818›Full record

ReviewLife (Basel, Switzerland)2013

Formaldehyde-a key monad of the biomolecular system.

Christian R Noe, Jerome Freissmuth, Peter Richter, Christian Miculka, Bodo Lachmann, Simon Eppacher

Abstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Prebiotic Syntheses Under Shock in the Water - Formamide - Potassium Bicarbonate - Sodium Hydroxide System.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Christian R NoeDepartment of Medicinal Chemistry, Faculty of Life Science University of Vienna, Althanstr. 14, Vienna 1090, Austria. christian.noe@univie.ac.at.
Jerome FreissmuthDepartment of Pharmaceutical Chemistry, University of Frankfurt, Max-von-Laue-Str. 9, Frankfurt D-60438, Germany. jfre@tetragon-chemie.com.
Peter RichterDepartment of Pharmaceutical Chemistry, University of Frankfurt, Max-von-Laue-Str. 9, Frankfurt D-60438, Germany. peter.richter@aqura.de.
Christian MiculkaDepartment of Pharmaceutical Chemistry, University of Frankfurt, Max-von-Laue-Str. 9, Frankfurt D-60438, Germany. christian.miculka@hotmail.com.
Bodo LachmannDepartment of Medicinal Chemistry, Faculty of Life Science University of Vienna, Althanstr. 14, Vienna 1090, Austria. bodo.lachmann@univie.ac.at.
Simon EppacherDepartment of Medicinal Chemistry, Faculty of Life Science University of Vienna, Althanstr. 14, Vienna 1090, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Experiments will be presented and reviewed to support the hypothesis that the intrinsic reactivity of formaldehyde may lead to the formation of a rather comprehensive set of defined biomolecules, including D-glucose, thus fostering concepts of evolution considering the existence of a premetabolic system as a primordial step in the generation of life.

Identifiers

PMID25369818
PMCPMC4187169

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.