ArticlePloS one2014
Identification of novel factors involved in modulating motility of Salmonella enterica serotype typhimurium.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 70 citations in OpenAlex.
- How Salmonella Works Under Osmotic and Desiccation Stresses.Comprehensive reviews in food science and food safety · 2026Review
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- Phage resistance of Bordetella avium due to an altered cell wall results in increased susceptibility to the polypeptide antibiotics colistin and polymyxin B.Scientific reports · 2025Article
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- Phenotypic and genotypic characterization of antimicrobial resistance and virulence profiles ofMicrobiology spectrum · 2025Article
- Sensitivity of dairy calfMicrobiology spectrum · 2024Article
- The origins of haplotype 58 (H58) Salmonella enterica serovar Typhi.Communications biology · 2024Article
- Genomic and phenotypic comparison of two variants of multidrug-resistantFrontiers in microbiology · 2023Article
- YeiE Regulates Motility and Gut Colonization in Salmonella enterica Serotype Typhimurium.mBio · 2021Article
- Sulfate Import inInfection and immunity · 2021Article
- Article
- Molecular and phenotypic characterization of Salmonella Typhimurium monophasic variant (1,4,[5],12:i:-) from Colombian clinical isolatesBiomedica : revista del Instituto Nacional de Salud · 2020Article
- Identification of Novel Genes Mediating Survival ofFrontiers in microbiology · 2020Article
- Monitoring Biofilm Formation and Microbial Interactions that May Occur During aMicroorganisms · 2019Article
- Loss of the Two-Component System TctD-TctE inmSphere · 2019Article
- A Family of Small Intrinsically Disordered Proteins Involved in Flagellum-Dependent Motility in Salmonella enterica.Journal of bacteriology · 2019Article
- A Novel Single Domain Antibody Targeting FliC Flagellin ofFrontiers in microbiology · 2019Article
- The Salmonella type-3 secretion system-1 and flagellar motility influence the neutrophil respiratory burst.PloS one · 2018Article
- A Comprehensive Assessment of the Genetic Determinants in Salmonella Typhimurium for Resistance to Hydrogen Peroxide Using Proteogenomics.Scientific reports · 2017Article
- Public health surveillance in the UK revolutionises our understanding of the invasive Salmonella Typhimurium epidemic in Africa.Genome medicine · 2017Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
Salmonella enterica serotype Typhimurium can move through liquid using swimming motility, and across a surface by swarming motility. We generated a library of targeted deletion mutants in Salmonella Typhimurium strain ATCC14028, primarily in genes specific to Salmonella, that we have previously described. In the work presented here, we screened each individual mutant from this library for the ability to move away from the site of inoculation on swimming and swarming motility agar. Mutants in genes previously described as important for motility, such as flgF, motA, cheY are do not move away from the site of inoculation on plates in our screens, validating our approach. Mutants in 130 genes, not previously known to be involved in motility, had altered movement of at least one type, 9 mutants were severely impaired for both types of motility, while 33 mutants appeared defective on swimming motility plates but not swarming motility plates, and 49 mutants had reduced ability to move on swarming agar but not swimming agar. Finally, 39 mutants were determined to be hypermotile in at least one of the types of motility tested. Both mutants that appeared non-motile and hypermotile on plates were assayed for expression levels of FliC and FljB on the bacterial surface and many of them had altered levels of these proteins. The phenotypes we report are the first phenotypes ever assigned to 74 of these open reading frames, as they are annotated as 'hypothetical genes' in the Typhimurium genome.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.