Evidence map›Paper›PMID 25369069›Full record

ArticleJournal of medicinal food2015

Diuretic and Anti-Inflammatory Activities of the Microencapsulated Acrocomia aculeata (Arecaceae) Oil on Wistar Rats.

Caroline Honaiser Lescano, Renan Donomae Iwamoto, Eliana Janet Sanjinez-Argandoña, Cândida Aparecida Leite Kassuya

Open access · greenAbstract read
In one paragraph

Article in Journal of medicinal food, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 50 citations in OpenAlex.

  1. Molecules (Basel, Switzerland) · 2026
    Article
  2. Review
  3. Beilstein journal of nanotechnology · 2025
    Article
  4. Article
  5. Article
  6. Molecules (Basel, Switzerland) · 2020
    Article
  7. Oxidative medicine and cellular longevity · 2020
    Article
  8. Therapeutic Potential of Brazilian CerradoMolecules (Basel, Switzerland) · 2018
    Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Caroline Honaiser Lescano1Faculty of Food Engineering, Federal University of Grande Dourados, Dourados, Brazil.
Renan Donomae Iwamoto2Faculty of Health Sciences, Federal University of Grande Dourados, Dourados, Brazil.
Eliana Janet Sanjinez-Argandoña1Faculty of Food Engineering, Federal University of Grande Dourados, Dourados, Brazil.
Cândida Aparecida Leite Kassuya2Faculty of Health Sciences, Federal University of Grande Dourados, Dourados, Brazil.
Universidade Federal da Grande Dourados · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acrocomia aculeata, popularly known as "bocaiuva," is widely acknowledged in culinary and traditional medicines to treat cardiovascular diseases, a combined effect with diuretics that are also used for hypertension. However, there are no scientific data published to support its use as functional food and its ethnopharmacological use. This study intended to determine the composition of fatty acids of the pulp oil and evaluate the diuretic action and anti-inflammatory activity of the in natura and microencapsulated oil orally administrated on rats. The obtained results confirm the prevalence of monounsaturated fatty acids (68.51%), especially oleic acid (65.68%±1.05%), in the oil from the bocaiuva pulp. The in natura A. aculeata oil has diuretic (P<.01) and anti-inflammatory potential, which promoted a marked inhibition on the hind paw edema induced by carrageenan (67%±7% after 2 h) (P<.01). In addition, results show that the oral administration of the bocaiuva oil at 300 (P<.05) and 700 (P<.05) mg/kg doses significantly inhibited the leukocyte migration induced by carrageenan to the pleural cavity in rats. The inhibitions equaled 91%±3% and 81%±16%, respectively. The microencapsulated oil also showed antiedematogenic (P<.01) as well as diuretic activities (P<.01). The microencapsulation by complex coacervation was shown to be a technique that favors the bioavailability and preservation of bioactive components of the bocaiuva oil.

Indexed as

PhytotherapyAnimalsAntihypertensive AgentsAnti-Inflammatory AgentsArecaceaeCarrageenanCell MovementDiureticsDrug CompoundingEdemaFruitInflammationLeukocytesMaleOleic AcidPlant OilsAntihypertensive AgentsAnti-Inflammatory AgentsCarrageenanDiureticsOleic AcidPlant Oilsbioactivityfatty acidsmicrocapsule

Identifiers

PMID25369069
PMCPMC4458740
OpenAlexW1981123683

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.