Evidence map›Paper›PMID 25368869›Full record

ReviewFrontiers in bioengineering and biotechnology2014

Enhancing stress-resistance for efficient microbial biotransformations by synthetic biology.

Haiyang Jia, Yanshuang Fan, Xudong Feng, Chun Li

Abstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Recent advances of pH homeostasis mechanisms in Corynebacterium glutamicum.World journal of microbiology & biotechnology · 2019
    Review
  6. Article
  7. Article
  8. Review
  9. PprM, a Cold Shock Domain-Containing Protein fromFrontiers in microbiology · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Haiyang JiaDepartment of Biological Engineering, School of Life Science, Beijing Institute of Technology , Beijing , China.
Yanshuang FanDepartment of Biological Engineering, School of Life Science, Beijing Institute of Technology , Beijing , China.
Xudong FengDepartment of Biological Engineering, School of Life Science, Beijing Institute of Technology , Beijing , China.
Chun LiDepartment of Biological Engineering, School of Life Science, Beijing Institute of Technology , Beijing , China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemical conversions mediated by microorganisms, otherwise known as microbial biotransformations, are playing an increasingly important role within the biotechnology industry. Unfortunately, the growth and production of microorganisms are often hampered by a number of stressful conditions emanating from environment fluctuations and/or metabolic imbalances such as high temperature, high salt condition, strongly acidic solution, and presence of toxic metabolites. Therefore, exploring methods to improve the stress tolerance of host organisms could significantly improve the biotransformation process. With the help of synthetic biology, it is now becoming feasible to implement strategies to improve the stress-resistance of the existing hosts. This review summarizes synthetic biology efforts to enhance the efficiency of biotransformations by improving the robustness of microbes. Particular attention will be given to strategies at the cellular and the microbial community levels.

Indexed as

biotransformationrobustnessstress conditionstress-resistancesynthetic biology

Identifiers

PMID25368869
PMCPMC4202804

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.