Evidence map›Paper›PMID 25368641›Full record

ReviewNeural regeneration research2014

Extracellular matrices, artificial neural scaffolds and the promise of neural regeneration.

Christian B Ricks, Samuel S Shin, Christopher Becker, Ramesh Grandhi

Open access · goldAbstract readReview
In one paragraph

Review in Neural regeneration research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. A State-of-the-Art of Functional Scaffolds for 3D Nervous Tissue Regeneration.Frontiers in bioengineering and biotechnology · 2021
    Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Facial nerve paralysis in children.World journal of clinical cases · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Christian B RicksDepartment of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Samuel S ShinDepartment of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Christopher BeckerUniversity of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Ramesh GrandhiDepartment of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
University of Pittsburgh · USNeurological Surgery · USUniversity of Pittsburgh Medical Center · US

Funding

The Effects of Traumatic Brain Injury in Alpha Synuclein and Dopamine RegulationF30NS067731 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SHIN, SAMUEL · 2010 to 2012
$135k
NINDS NIH HHS F30 NS067731
6 · The paper itself

Abstract

Over last 20 years, extracellular matrices have been shown to be useful in promoting tissue regeneration. Recently, they have been used and have had success in achieving neurogenesis. Recent developments in extracellular matrix design have allowed their successful in vivo incorporation to engender an environment favorable for neural regeneration in animal models. Promising treatments under investigation include manipulation of the intrinsic extracellular matrix and incorporation of engineered naometer-sized scaffolds through which inhibition of molecules serving as barriers to neuroregeneration and delivery of neurotrophic factors and/or cells for successful tissue regeneration can be achieved. Further understanding of the changes incurred within the extracellular matrix following central nervous system injury will undoubtedly help design a clinically efficacious extracellular matrix scaffold that can mitigate or reverse neural degeneration in the clinical setting.

Indexed as

extracellular matrixneural stem cellsneurogenesisscaffolds

Identifiers

PMID25368641
PMCPMC4211196
OpenAlexW2002100949

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.