ReviewFrontiers in endocrinology2014
Constitutional thinness and anorexia nervosa: a possible misdiagnosis?
Review in Frontiers in endocrinology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Underweight but not underfat: is fat-free mass a key factor in constitutionally thin women?European journal of clinical nutrition · 2021Pooled it
- Is constitutional thinness really different from anorexia nervosa? A systematic review and meta-analysis.Reviews in endocrine & metabolic disorders · 2021Pooled it
- Metabolic and pathophysiological characterization of constitutional thinness.Journal of endocrinological investigation · 2026Article
- Bone mineral density and bone turnover in adolescent girls with anorexia nervosa: a 3-year retrospective cohort study.Frontiers in endocrinology · 2026Article
- Loss of Sult1a1 reduces body weight and increases browning of white adipose tissue.Frontiers in endocrinology · 2024Article
- Persistent thinness and anorexia nervosa differ on a genomic level.European journal of human genetics : EJHG · 2024Article
- Systematic review of prospective studies assessing risk factors to predict anorexia nervosa onset.Journal of eating disorders · 2023Review
- Resistance to lean mass gain in constitutional thinness in free-living conditions is not overpassed by overfeeding.Journal of cachexia, sarcopenia and muscle · 2020Article
- A pilot study on the effect of isotretinoin on serum etonogestrel concentrations in contraceptive implant users.Contraception · 2020Article
- The unidentified hormonal defense against weight gain.PLoS biology · 2020Article
- The Ghrelin-AgRP Neuron Nexus in Anorexia Nervosa: Implications for Metabolic and Behavioral Adaptations.Frontiers in nutrition · 2019Review
- Assessment of Biochemical Bone Turnover Markers and Bone Mineral Density in Thin and Normal-Weight Children.Cartilage · 2018Article
- Increasing variability of body mass and health correlates in Swiss conscripts, a possible role of relaxed natural selection?Evolution, medicine, and public health · 2018Article
- Adult adiposity and risk of early menopause.Human reproduction (Oxford, England) · 2017Article
- Editorial: neurological and psychiatric disorders in endocrine diseases.Frontiers in endocrinology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Clinical and biological aspects of restrictive anorexia nervosa (R-AN) are well documented. More than 10,000 articles since 1911 and more than 600 in 2013 have addressed R-AN psychiatric, somatic, and biological aspects. Genetic background, ineffectiveness of appetite regulating hormones on refeeding process, bone loss, and place of amenorrhea in the definition are widely discussed and reviewed. Oppositely, constitutional thinness (CT) is an almost unknown entity. Only 32 articles have been published on this topic since 1953. Similar symptoms associating low body mass index, low fat, and bone mass are reported in both CT and R-AN subjects. Conversely, menses are preserved in CT women and almost the entire hormonal profile is normal, except for leptin and PYY. The aim of the present review is to alert the clinician on the confusing clinical presentation of these two situations, a potential source of misdiagnosis, especially since R-AN definition has changed in DSM5.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.