ArticleMolecular biology of the cell2014
Emergent mechanics of biological structures.
Article in Molecular biology of the cell, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- The Organism as a System: Insights from Paul Weiss.Acta biotheoretica · 2026Article
- An adaptable, self-organizing, single-cell morphology circuit optimizes suctorian predatory trap structure.Current biology : CB · 2026Article
- A self-organizing single-cell morphology circuit optimizesbioRxiv : the preprint server for biology · 2025Article
- Metareview: a survey of active matter reviews.The European physical journal. E, Soft matter · 2025Review
- Deciphering Mechanochemical Influences of Emergent Actomyosin Crosstalk Using QCM-D.Cellular and molecular bioengineering · 2025Article
- Measuring emergent mechanical changes in cytoskeletal ensemblesFrontiers in cell and developmental biology · 2025Article
- Deciphering Mechanochemical Influences of Emergent Actomyosin Crosstalk using QCM-D.bioRxiv : the preprint server for biology · 2024Article
- Studying Biomolecular Protein Complexes via Origami and 3D-Printed Models.International journal of molecular sciences · 2024Article
- Amorphous entangled active matter.Soft matter · 2023Article
- Scanning Tunneling Microscopy of Biological Structures: An Elusive Goal for Many Years.Nanomaterials (Basel, Switzerland) · 2022Review
- 3D nanomechanical mapping of subcellular and sub-nuclear structures of living cells by multi-harmonic AFM with long-tip microcantilevers.Scientific reports · 2022Article
- Article
- Actin crosslinker competition and sorting drive emergent GUV size-dependent actin network architecture.Communications biology · 2021Article
- Spatially-resolved nanometer-scale measurement of cartilage extracellular matrix mobility.Osteoarthritis and cartilage · 2021Article
- Atomic force microscopy for revealing micro/nanoscale mechanics in tumor metastasis: from single cells to microenvironmental cues.Acta pharmacologica Sinica · 2021Review
- What Is the Right Mechanical Readout for Understanding the Mechanobiology of the Immune Response?Frontiers in cell and developmental biology · 2021Article
- Article
- Force Spectroscopy and Beyond: Innovations and Opportunities.Biophysical journal · 2018Review
- The Spindle: Integrating Architecture and Mechanics across Scales.Trends in cell biology · 2018Review
- The effects of mechanical strain on mouse eye lens capsule and cellular microstructure.Molecular biology of the cell · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Mechanical force organizes life at all scales, from molecules to cells and tissues. Although we have made remarkable progress unraveling the mechanics of life's individual building blocks, our understanding of how they give rise to the mechanics of larger-scale biological structures is still poor. Unlike the engineered macroscopic structures that we commonly build, biological structures are dynamic and self-organize: they sculpt themselves and change their own architecture, and they have structural building blocks that generate force and constantly come on and off. A description of such structures defies current traditional mechanical frameworks. It requires approaches that account for active force-generating parts and for the formation of spatial and temporal patterns utilizing a diverse array of building blocks. In this Perspective, we term this framework "emergent mechanics." Through examples at molecular, cellular, and tissue scales, we highlight challenges and opportunities in quantitatively understanding the emergent mechanics of biological structures and the need for new conceptual frameworks and experimental tools on the way ahead.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.