ReviewCold Spring Harbor perspectives in medicine2014
The spectrum of fungi that infects humans.
Review in Cold Spring Harbor perspectives in medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 155 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
155 citing papers in PubMed.
- Trial
- Large-scale genome re-annotation uncovers pathogen-specific lncRNA regulators of fungal growth and virulence.PLoS pathogens · 2026Article
- Inhibitors of spore germination act against diverse human fungal pathogens.bioRxiv : the preprint server for biology · 2026Article
- In Silico Discovery and in vitro Evaluation of the Antifungal and Cytotoxicity Properties of Zeaxanthin and β-Carotene.Current microbiology · 2026Article
- Indoor air bacterial and fungal burden in the environment of an atopic child: implications for elevated urine mycotoxin levels.Arhiv za higijenu rada i toksikologiju · 2026Article
- Use of a human immortalized microglia cell line to study recognition, phagocytosis, and intracellular survival ofmSphere · 2026Article
- Article
- Evaluating the Antifungal Potential of Autophagy-Related Protein 4 (ATG4) Inhibitors against Human Fungal Pathogens.Journal of microbiology and biotechnology · 2025Article
- Article
- Expansion of the functional genomics GRACE library reveals genes relevant for temperature-dependent fitness in Candida albicans.PLoS biology · 2025Article
- Microbial Keratinolysis: Eco-Friendly Valorisation of Keratinous Waste into Functional Peptides.Microorganisms · 2025Review
- Interplay between fungal infections and autoimmunity: mechanisms and therapeutic perspectives.EMBO molecular medicine · 2025Review
- Disseminated candidiasis on FDG-PET/CT.Molecular imaging and radionuclide therapy · 2025Article
- Human immunity to fungal infections.The Journal of experimental medicine · 2025Review
- Synthesis, Physicochemical Properties and Anti-Fungal Activities of NewInternational journal of molecular sciences · 2025Article
- Antifungal Natural Products Originating from Endophytic and Rhizospheric Microbes Isolated from Coastal Vegetation.Journal of xenobiotics · 2025Review
- Fungal Infections in Kidney Transplant Recipients: A Comprehensive Narrative Review.Microorganisms · 2025Review
- Phytochemical profiling and bioactive potential of bael gum using UHPLC-Q-TOF-MS: a novel nutraceutical source.Frontiers in nutrition · 2025Article
- Size-resolved fungal bioaerosol diversity over an Indian agricultural field and their ecosystem-health implications.Frontiers in microbiology · 2025Article
- Taxonomic diversity in the global wheat phyllosphere mycobiome - a meta analysis.Frontiers in plant science · 2025Article
95 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Few among the millions of fungal species fulfill four basic conditions necessary to infect humans: high temperature tolerance, ability to invade the human host, lysis and absorption of human tissue, and resistance to the human immune system. In previously healthy individuals, invasive fungal disease is rare because animals' sophisticated immune systems evolved in constant response to fungal challenges. In contrast, fungal diseases occur frequently in immunocompromised patients. Paradoxically, successes of modern medicine have put increasing numbers of patients at risk for invasive fungal infections. Uncontrolled HIV infection additionally makes millions vulnerable to lethal fungal diseases. A concerted scientific and social effort is needed to meet these challenges.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.