ArticleClinical and experimental nephrology2015
Is the mean platelet volume a predictive marker for the diagnosis of acute pyelonephritis in children?
Article in Clinical and experimental nephrology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Procalcitonin, C-reactive protein, and erythrocyte sedimentation rate for the diagnosis of acute pyelonephritis in children.The Cochrane database of systematic reviews · 2020Pooled it
- Diagnostic accuracy of mean platelet volume in cirrhotic patients with spontaneous bacterial peritonitis presented to the emergency department.Caspian journal of internal medicine · 2025Article
- The association between mean platelet volume and poor outcome in patients with COVID-19: Systematic review, meta-analysis, and meta-regression.Journal of the Intensive Care Society · 2023Article
- Mean platelet volume is the most valuable hematologic parameter in differentiating testicular torsion from epididymitis within the golden time.Translational andrology and urology · 2022Article
- Is mean platelet volume a predictive marker for the diagnosis of COVID-19 in children?International journal of clinical practice · 2021Article
- Host and Bacterial Markers that Differ in Children with Cystitis and Pyelonephritis.The Journal of pediatrics · 2019Article
- Hemoglobin level is a more predictive diagnostic marker for acute pyelonephritis than mean platelet volume.Clinical and experimental nephrology · 2016Article
- Usefulness of neutrophil-lymphocyte ratio in young children with febrile urinary tract infection.Korean journal of pediatrics · 2016Article
- Mean platelet volume in young children with urinary tract infection.Scientific reports · 2015Article
- Mean platelet volume as a novel predictor of systemic inflammatory response in cirrhotic patients with culture-negative neutrocytic ascites.World journal of hepatology · 2015Article
- Neutrophil-to-lymphocyte ratio and mean platelet volume can be useful markers to predict sepsis in children.Pakistan journal of medical sciencesArticle
- The role of the mean platelet volume and neutrophil-to-lymphocyte ratio in peritonsillar abscesses.Brazilian journal of otorhinolaryngologyArticle
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcute pyelonephritis (APN) can lead to renal scar formation, high blood pressure, and end-stage renal failure. Prompt and early diagnosis of APN is important for preventing future complications. Our goal was to study the mean platelet volume (MPV) as a predictor of APN in children.
methodsThe records of 43 patients with APN and 51 patients with a lower urinary tract infection (UTI) were investigated prospectively. APN was confirmed using radioactive nuclide 99mTc-DMSA scanning. The white blood cell (WBC) count, erythrocyte sedimentation rate (ESR), serum C-reactive protein (CRP), and MPV of both groups were measured and compared.
resultsThe WBC count, MPV and ESR values, and the serum concentration of CRP were higher in the APN group than in the lower UTI group (p < 0.05). In the children with APN, the optimal cut-off value for the MPV was 8.2 fl [area under the curve (AUC): 0.906], with sensitivity of 81.4 % and specificity of 86.3 %. The MPV was associated with APN (p = 0.001), and the sensitivity and specificity of the MPV for the diagnosis of APN were higher than those of the other inflammation markers. MPV > 8.2 fl yielded an adjusted OR of 7.8 (95 % CI 3.3-18.4, p < 0.001) for APN. MPV > 8.2 fl was significantly associated with late renal scar formation (adjusted OR 5.7, 95 % CI 2.3-13.8, p < 0.001).
conclusionThe MPV is a fast and reliable measurement with considerable predictive value for the diagnosis of APN and renal scars, and its predictive capacity is better than that of CRP, ESR, and WBC values.
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