ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2015
Evaluation of image reconstruction algorithms encompassing Time-Of-Flight and Point Spread Function modelling for quantitative cardiac PET: phantom studies.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Fast and Accurate Gamma Imaging System Calibration Based on Deep Denoising Networks and Self-Adaptive Data Clustering.Sensors (Basel, Switzerland) · 2023Article
- Pitfalls on PET/CT Due to Artifacts and Instrumentation.Seminars in nuclear medicine · 2021Review
- The Importance of Time-of-Flight Reconstruction and Point Spread Modeling in the Measurement of Myocardial Blood Flow Parameters.Current cardiology reports · 2021Review
- TOF-PET Image Reconstruction With Multiple Timing Kernels Applied on Cherenkov Radiation in BGO.IEEE transactions on radiation and plasma medical sciences · 2020Article
- Two-crossed-polarizers based optical property modulation method for ionizing radiation detection for positron emission tomography.Physics in medicine and biology · 2019Article
- Impact of pharmacological stress agent on patient motion during rubidium-82 myocardial perfusion PET/CT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- Motion Correction and Its Impact on Absolute Myocardial Blood Flow Measures with PET.Current cardiology reports · 2018Review
- Cardiac PET/CT with Rb-82: optimization of image acquisition and reconstruction parameters.EJNMMI physics · 2017Article
- How to reconstruct dynamic cardiac PET data?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Quantification of myocardial blood flow with (82)Rb: Validation with (15)O-water using time-of-flight and point-spread-function modeling.EJNMMI research · 2016Article
- A promising new mechanism of ionizing radiation detection for positron emission tomography: modulation of optical properties.Physics in medicine and biology · 2016Article
- Simultaneous reconstruction of attenuation and activity in cardiac PET can remove CT misalignment artifacts.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016Article
- Precision and accuracy of clinical quantification of myocardial blood flow by dynamic PET: A technical perspective.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo perform kinetic modelling quantification, PET dynamic data must be acquired in short frames, where different critical conditions are met. The accuracy of reconstructed images influences quantification. The added value of Time-Of-Flight (TOF) and Point Spread Function (PSF) in cardiac image reconstruction was assessed.
methodsA static phantom was used to simulate two extreme conditions: (i) the bolus passage and (ii) the steady uptake. Various count statistics and independent noise realisations were considered. A moving phantom filled with two different radionuclides was used to simulate: (i) a great range of contrasts and (ii) the cardio/respiratory motion. Analytical and iterative reconstruction (IR) algorithms also encompassing TOF and PSF modelling were evaluated.
resultsBoth analytic and IR algorithms provided good results in all the evaluated conditions. The amount of bias introduced by IR was found to be limited. TOF allowed faster convergence and lower noise levels. PSF achieved near full myocardial activity recovery in static conditions. Motion degraded performances, but the addition of both TOF and PSF maintained the best overall behaviour.
conclusionsIR accounting for TOF and PSF can be recommended for the quantification of dynamic cardiac PET studies as they improve the results compared to analytic and standard IR.
Indexed as
Identifiers
25367452What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.