Evidence map›Paper›PMID 25366684›Full record

Trial reportJournal of clinical oncology : official journal of the American Society of Clinical Oncology2014

Increasing cardiomyopathy screening in at-risk adult survivors of pediatric malignancies: a randomized controlled trial.

Melissa M Hudson, Wendy Leisenring, Kayla K Stratton, Nina Tinner, Brenda D Steen, Susan Ogg, Linda Barnes, Kevin C Oeffinger, Leslie L Robison, Cheryl L Cox

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Systematic Review of the Impact of Cancer Survivorship Care Plans on Health Outcomes and Health Care Delivery.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2018
    Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Trial
  7. Trial
  8. Trial
  9. Article
  10. Article
  11. Review
  12. Health Care Transitions Among Adolescents and Young Adults With Cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024
    Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Artificial intelligence opportunities in cardio-oncology: Overview with spotlight on electrocardiography.American heart journal plus : cardiology research and practice · 2022
    Article
  20. Awareness of diagnosis, treatment and risk of late effects in Chinese survivors of childhood cancer in Hong Kong.Health expectations : an international journal of public participation in health care and health policy · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Melissa M HudsonMelissa M. Hudson, Nina Tinner, Brenda D. Steen, Susan Ogg, Linda Barnes, Leslie L. Robison, and Cheryl L. Cox, St Jude Children's Research Hospital, Memphis, TN; Wendy Leisenring and Kayla K. Stratton, Fred Hutchinson Cancer Research Center, Seattle, WA; and Kevin C. Oeffinger, Memorial Sloan Kettering Cancer Center, New York, NY. melissa.hudson@stjude.org.
Wendy LeisenringMelissa M. Hudson, Nina Tinner, Brenda D. Steen, Susan Ogg, Linda Barnes, Leslie L. Robison, and Cheryl L. Cox, St Jude Children's Research Hospital, Memphis, TN; Wendy Leisenring and Kayla K. Stratton, Fred Hutchinson Cancer Research Center, Seattle, WA; and Kevin C. Oeffinger, Memorial Sloan Kettering Cancer Center, New York, NY.
Kayla K StrattonMelissa M. Hudson, Nina Tinner, Brenda D. Steen, Susan Ogg, Linda Barnes, Leslie L. Robison, and Cheryl L. Cox, St Jude Children's Research Hospital, Memphis, TN; Wendy Leisenring and Kayla K. Stratton, Fred Hutchinson Cancer Research Center, Seattle, WA; and Kevin C. Oeffinger, Memorial Sloan Kettering Cancer Center, New York, NY.
Nina TinnerMelissa M. Hudson, Nina Tinner, Brenda D. Steen, Susan Ogg, Linda Barnes, Leslie L. Robison, and Cheryl L. Cox, St Jude Children's Research Hospital, Memphis, TN; Wendy Leisenring and Kayla K. Stratton, Fred Hutchinson Cancer Research Center, Seattle, WA; and Kevin C. Oeffinger, Memorial Sloan Kettering Cancer Center, New York, NY.
Brenda D SteenMelissa M. Hudson, Nina Tinner, Brenda D. Steen, Susan Ogg, Linda Barnes, Leslie L. Robison, and Cheryl L. Cox, St Jude Children's Research Hospital, Memphis, TN; Wendy Leisenring and Kayla K. Stratton, Fred Hutchinson Cancer Research Center, Seattle, WA; and Kevin C. Oeffinger, Memorial Sloan Kettering Cancer Center, New York, NY.
Susan OggMelissa M. Hudson, Nina Tinner, Brenda D. Steen, Susan Ogg, Linda Barnes, Leslie L. Robison, and Cheryl L. Cox, St Jude Children's Research Hospital, Memphis, TN; Wendy Leisenring and Kayla K. Stratton, Fred Hutchinson Cancer Research Center, Seattle, WA; and Kevin C. Oeffinger, Memorial Sloan Kettering Cancer Center, New York, NY.
Linda BarnesMelissa M. Hudson, Nina Tinner, Brenda D. Steen, Susan Ogg, Linda Barnes, Leslie L. Robison, and Cheryl L. Cox, St Jude Children's Research Hospital, Memphis, TN; Wendy Leisenring and Kayla K. Stratton, Fred Hutchinson Cancer Research Center, Seattle, WA; and Kevin C. Oeffinger, Memorial Sloan Kettering Cancer Center, New York, NY.
Kevin C OeffingerMelissa M. Hudson, Nina Tinner, Brenda D. Steen, Susan Ogg, Linda Barnes, Leslie L. Robison, and Cheryl L. Cox, St Jude Children's Research Hospital, Memphis, TN; Wendy Leisenring and Kayla K. Stratton, Fred Hutchinson Cancer Research Center, Seattle, WA; and Kevin C. Oeffinger, Memorial Sloan Kettering Cancer Center, New York, NY.
Leslie L RobisonMelissa M. Hudson, Nina Tinner, Brenda D. Steen, Susan Ogg, Linda Barnes, Leslie L. Robison, and Cheryl L. Cox, St Jude Children's Research Hospital, Memphis, TN; Wendy Leisenring and Kayla K. Stratton, Fred Hutchinson Cancer Research Center, Seattle, WA; and Kevin C. Oeffinger, Memorial Sloan Kettering Cancer Center, New York, NY.
Cheryl L CoxMelissa M. Hudson, Nina Tinner, Brenda D. Steen, Susan Ogg, Linda Barnes, Leslie L. Robison, and Cheryl L. Cox, St Jude Children's Research Hospital, Memphis, TN; Wendy Leisenring and Kayla K. Stratton, Fred Hutchinson Cancer Research Center, Seattle, WA; and Kevin C. Oeffinger, Memorial Sloan Kettering Cancer Center, New York, NY.

Funding

Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI CHARLES ROBERTS · 1985 to 2026
$166.9M
Mach-LETSGO: Machine-LEarning of Treatment, Survey, and Genetics towards Obtaining Correct Classification of Chronic Conditions in Adult Survivors in the Childhood Cancer Survivor Study - CCSS SupplU24CA055727 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Gregory Armstrong · 1999 to 2026
$96.7M
Evaluation of Cardiovascular Outcomes Among Childhood Cancer SurvivorsR01NR011322 · NINR · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI COX, CHERYL LORANE, HUDSON, MELISSA M · 2009 to 2012
$2.1M
CHILDHOOD CANCER SURVIVOR STUDYU01CA055727 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI ROBISON, LESLIE L · 1993 to 1999
–
NCI NIH HHS CA21765NCI NIH HHS CA55727NCI NIH HHS P30 CA021765NCI NIH HHS U24 CA055727NINR NIH HHS R01 NR011322
6 · The paper itself

Abstract

purposeTo determine whether the addition of advanced-practice nurse (APN) telephone counseling to a printed survivorship care plan (SCP) significantly increases the proportion of at-risk survivors who complete cardiomyopathy screening. PATIENTS AND

methodsSurvivors age ≥ 25 years participating in the Childhood Cancer Survivor Study who received cardiotoxic therapy and reported no history of cardiomyopathy screening in the previous 5 years were eligible for enrollment. The 472 participants (mean age, 40.1 years; range, 25.0 to 59.0; 53.3% women) were randomly assigned to either standard care, consisting of an SCP summarizing cancer treatment and cardiac health screening recommendations (n = 234), or standard care plus two APN telephone counseling sessions (n = 238). The primary outcome-completion of cardiomyopathy screening within 1 year-was validated by medical records and compared between the two arms using adjusted relative risks (RRs) with 95% CIs.

resultsParticipants in the standard and APN counseling groups were not statistically different by demographic or clinical characteristics. At the time of 1-year follow-up, 107 (52.2%) of 205 survivors in the APN group completed screening compared with 46 (22.3%) of 206 survivors in the non-APN group (P < .001). With adjustment for sex, age (< 30 v ≥ 30 years), and Children's Oncology Group-recommended screening frequency group (annual, 2 years, or 5 years), survivors in the APN group were > 2× more likely than those in the control group to complete the recommended cardiomyopathy screening (RR, 2.31; 95% CI, 1.74 to 3.07).

conclusionThe addition of telephone counseling to an SCP with cardiac health screening recommendations increases cardiomyopathy screening in at-risk survivors.

Indexed as

AdultAdvanced Practice NursingCardiomyopathiesChildEchocardiographyFemaleFollow-Up StudiesHumansMaleMiddle AgedNeoplasmsRiskSurvival RateSurvivorsTelemedicineTreatment Outcome

Identifiers

PMID25366684
PMCPMC4251960

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.