ArticleHuman brain mapping2015
The mirror neuron system and the strange case of Broca's area.
Article in Human brain mapping, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Object-oriented hand dexterity and grasping abilities, from the animal quarters to the neurosurgical OR: a systematic review of the underlying neural correlates in non-human, human primate and recent findings in awake brain surgery.Frontiers in integrative neuroscience · 2024Pooled it
- Efficacy of a Rehabilitation Treatment Using Action Observation Therapy Enhanced by Muscle Synergy-Derived Electrical Stimulation (OTHELLO) in Post-Stroke Patients: A RCT Study Protocol.Journal of central nervous system disease · 2025Article
- Action observation and imitation: Corticospinal responses and hemispheric dominance.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Connectivity Reveals the Relationships between Human Brain Areas Associated with High-Level Linguistic Processing and Macaque Brain Areas.Tomography (Ann Arbor, Mich.) · 2024Article
- The widespread action observation/execution matching system for facial expression processing.Human brain mapping · 2023Article
- Occupation-modulated language networks and its lateralization: A resting-state fMRI study of seafarers.Frontiers in human neuroscience · 2023Article
- Spatio-Temporal Neural Dynamics of Observing Non-Tool Manipulable Objects and Interactions.Sensors (Basel, Switzerland) · 2022Article
- How Do We Motorically Resonate in Aging? A Compensatory Role of Prefrontal Cortex.Frontiers in aging neuroscience · 2021Article
- Sensitivity of occipito-temporal cortex, premotor and Broca's areas to visible speech gestures in a familiar language.PloS one · 2020Article
- Preoperative transcranial magnetic stimulation for picture naming is reliable in mapping segments of the arcuate fasciculus.Brain communications · 2020Article
- Broca's Area as a Pre-articulatory Phonetic Encoder: Gating the Motor Program.Frontiers in human neuroscience · 2018Article
- The Mirror Neurons Network in Aging, Mild Cognitive Impairment, and Alzheimer Disease: A functional MRI Study.Frontiers in aging neuroscience · 2017Article
- Brain-to-brain hyperclassification reveals action-specific motor mapping of observed actions in humans.PloS one · 2017Article
- Walk like me, talk like me. The connection between mirror neurons and autism spectrum disorder.Neurosciences (Riyadh, Saudi Arabia) · 2016Article
- Divergent Human Cortical Regions for Processing Distinct Acoustic-Semantic Categories of Natural Sounds: Animal Action Sounds vs. Vocalizations.Frontiers in neuroscience · 2016Article
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mirror neurons, originally described in the monkey premotor area F5, are embedded in a frontoparietal network for action execution and observation. A similar Mirror Neuron System (MNS) exists in humans, including precentral gyrus, inferior parietal lobule, and superior temporal sulcus. Controversial is the inclusion of Broca's area, as homologous to F5, a relevant issue in light of the mirror hypothesis of language evolution, which postulates a key role of Broca's area in action/speech perception/production. We assess "mirror" properties of this area by combining neuroimaging and intraoperative neurophysiological techniques. Our results show that Broca's area is minimally involved in action observation and has no motor output on hand or phonoarticulatory muscles, challenging its inclusion in the MNS. The presence of these functions in premotor BA6 makes this area the likely homologue of F5 suggesting that the MNS may be involved in the representation of articulatory rather than semantic components of speech.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.