Evidence map›Paper›PMID 25366494›Full record

ReviewPflugers Archiv : European journal of physiology2015

Gastrointestinal motility and its enteric actors in mechanosensitivity: past and present.

Bruno Mazet

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pflugers Archiv : European journal of physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Mechanosensing Piezo channels in gastrointestinal disorders.The Journal of clinical investigation · 2023
    Review
  3. Seasonal flexibility of the gut structure and physiology in Eremias multiocellata.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2023
    Article
  4. Mechanotransduction at the Plasma Membrane-Cytoskeleton Interface.International journal of molecular sciences · 2021
    Review
  5. Mechanotransduction in gastrointestinal smooth muscle cells: role of mechanosensitive ion channels.American journal of physiology. Gastrointestinal and liver physiology · 2021
    Review
  6. Review
  7. Article
  8. Article
  9. Role of BKBioMed research international · 2016
    Article
  10. Pediatric intestinal motility disorders.World journal of gastroenterology · 2015
    Review
  11. Transduction and encoding sensory information by skin mechanoreceptors.Pflugers Archiv : European journal of physiology · 2015
    Review
  12. A special issue on physiological aspects of mechanosensing.Pflugers Archiv : European journal of physiology · 2015
    Article
  13. Intestinal manometry: who needs it?Gastroenterology and hepatology from bed to bench · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Bruno MazetAix Marseille Université, CNRS, CRN2M UMR 7286, CS80011 Bd Pierre Dramard, 13344, Marseille Cedex 15, France, bruno.mazet@univ-amu.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coordinated contractions of the smooth muscle layers of the gastrointestinal (GI) tract are required to produce motor patterns that ensure normal GI motility. The crucial role of the enteric nervous system (ENS), the intrinsic ganglionated network located within the GI wall, has long been recognized in the generation of the main motor patterns. However, devising an appropriate motility requires the integration of informations emanating from the lumen of the GI tract. As already found more than half a century ago, the ability of the GI tract to respond to mechanical forces such as stretch is not restricted to neuronal mechanisms. Instead, mechanosensitivity is now recognized as a property of several non-neuronal cell types, the excitability of which is probably involved in shaping the motor patterns. This brief review gives an overview on how mechanosensitivity of different cell types in the GI tract has been established and, whenever available, on what ionic conductances are involved in mechanotransduction and their potential impact on normal GI motility.

Indexed as

AnimalsGastrointestinal MotilityHumansMechanotransduction, CellularModels, BiologicalMyocytes, Smooth Muscle

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.