Evidence map›Paper›PMID 25366266›Full record

ArticleMedical science monitor : international medical journal of experimental and clinical research2014

Atomic absorption spectrometry analysis of trace elements in degenerated intervertebral disc tissue.

Łukasz Kubaszewski, Anetta Zioła-Frankowska, Marcin Frankowski, Andrzej Nowakowski, Róża Czabak-Garbacz, Jacek Kaczmarczyk, Robert Gasik

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in Medical science monitor : international medical journal of experimental and clinical research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Retracted: Atomic Absorption Spectrometry Analysis of Trace Elements in Degenerated Intervertebral Disc Tissue.Medical science monitor : international medical journal of experimental and clinical research · 2021
    Article
  3. Article
  4. Article
  5. Protective effects ofBioscience reports · 2018
    Article
  6. Article
  7. Ginger (Avicenna journal of phytomedicine
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Łukasz KubaszewskiDepartment of Orthopaedic and Traumatology, W. Dega University Hospital, University of Medical Sciences, Poznań, Poland.
Anetta Zioła-FrankowskaDepartment of Water and Soil Analysis, Faculty of Chemistry, Adam Mickiewicz University in Poznań, Poznań, Poland.
Marcin FrankowskiDepartment of Water and Soil Analysis, Faculty of Chemistry, Adam Mickiewicz University in Poznań, Poznań, Poland.
Andrzej NowakowskiDepartment of Spine Surgery, Oncologic Orthopaedics and Traumatology, W. Dega University Hospital, University of Medical Sciences, Poznań, Poland.
Róża Czabak-GarbaczDepartment of Human Physiology, Medical University of Lublin, Lublin, Poland.
Jacek KaczmarczykDepartment of Orthopaedic and Traumatology, W. Dega University Hospital, University of Medical Sciences, Poznań, Poland.
Robert GasikClinic and Polyclinic of Neuroorthopedic and Neurology, Institute of Rheumatology, Warsaw, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFew studies have investigated trace elements (TE) in human intervertebral disc (IVD) tissue. Trace element presence can have diverse meanings: essential TE show the metabolic modalities of the tissue, while environmentally-related TE indicate pollution and tissue-specific absorption and accumulation. IVD is a highly specific compartment with impaired communication with adjacent bone. Analysis of TE in IVD provides new insights regarding tissue metabolism and IVD communication with other tissues. MATERIAL/

methodsThirty intervertebral discs were acquired from 22 patients during surgical treatment for degenerative disease. Atomic absorption spectrometry was used to evaluate the concentrations of Al, Cd, Pb, Cu, Ni, Mo, Mg, and Zn.

resultsAl, Pb, Cu, Mg, and Zn were detected in all samples. Pb was significantly positively correlated with age, and Ni concentration was weakly correlated with population count in the patient's place of residence. Only Cu was observed in higher concentrations in IVD compared to in other tissues. Significant positive correlations were observed between the following pairs: Mg/Zn, Mg/Al, Mg/Pb, Zn/Al, Zn/Pb, and Al/Pb. Negative correlations were observed between Mg/Cd, Zn/Cd, Mg/Mo, and Mo/Pb.

conclusionsThis study is one of few to profile the elements in intervertebral discs in patients with degenerative changes. We report significant differences between trace element concentrations in intervertebral discs compared to in other tissues. Knowledge of the TE accumulation pattern is vital for better understanding intervertebral disc nutrition and metabolism.

Indexed as

AdultAge FactorsHumansIntervertebral Disc DegenerationMiddle AgedSpectrophotometry, AtomicStatistics, NonparametricTrace ElementsTrace Elements

Identifiers

PMID25366266
PMCPMC4301216
OpenAlexW2130809522

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.