Evidence map›Paper›PMID 25366264›Full record

ReviewJournal of experimental & clinical cancer research : CR2014

Progress in oncolytic virotherapy for the treatment of thyroid malignant neoplasm.

Mingxu Guan, Gaetano Romano, Roberta Coroniti, Earl E Henderson

Open access · goldAbstract readReview
In one paragraph

Review in Journal of experimental & clinical cancer research : CR, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Anaplastic thyroid cancer: outcomes of trimodal therapy.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2021
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. ARE/SUZ12 dual specifically-regulated adenoviral TK/GCV system for CML blast crisis cells.Journal of experimental & clinical cancer research : CR · 2015
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mingxu GuanDepartment of Microbiology and Immunology, Temple University School of Medicine, Broad Street, 3400 N, Philadelphia, PA, USA. mingxuguan@gmail.com.
Gaetano RomanoDepartment of Microbiology and Immunology, Temple University School of Medicine, Broad Street, 3400 N, Philadelphia, PA, USA. gromano@temple.edu.
Roberta CoronitiDepartment of Biology, College of Science and Technology, Temple University, 12th Street, Philadelphia, PA, USA. robertacoroniti@hotmail.it.
Earl E HendersonDepartment of Microbiology and Immunology, Temple University School of Medicine, Broad Street, 3400 N, Philadelphia, PA, USA. eehender@temple.edu.
Temple University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyroid malignant neoplasm develops from follicular or parafollicular thyroid cells. A higher proportion of anaplastic thyroid cancer has an adverse prognosis. New drugs are being used in clinical treatment. However, for advanced thyroid malignant neoplasm such as anaplastic thyroid carcinoma, the major impediment to successful control of the disease is the absence of effective therapies. Oncolytic virotherapy has significantly progressed as therapeutics in recent years. The advance is that oncolytic viruses can be designed with biological specificity to infect, replicate and lyse tumor cells. Significant advances in virotherapy have being achieved to improve the accessibility, safety and efficacy of the treatment. Therefore, it is necessary to summarize and bring together the main areas covered by these investigations for the virotherapy of thyroid malignant neoplasm. We provide an overview of the progress in virotherapy research and clinical trials, which employ virotherapy for thyroid malignant neoplasm as well as the future prospect for virotherapy of thyroid malignant neoplasms.

Indexed as

AnimalsHost-Pathogen InteractionsHumansOncolytic VirotherapyOncolytic VirusesThyroid NeoplasmsTreatment Outcome

Identifiers

PMID25366264
PMCPMC4242545
OpenAlexW2125586463

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.