Evidence map›Paper›PMID 25365529›Full record

ReviewChemical reviews2014

Recent developments in drug discovery for leishmaniasis and human African trypanosomiasis.

Advait S Nagle, Shilpi Khare, Arun Babu Kumar, Frantisek Supek, Andriy Buchynskyy, Casey J N Mathison, Naveen Kumar Chennamaneni, Nagendar Pendem, Frederick S Buckner, Michael H Gelb and 1 more

Abstract readReview
In one paragraph

Review in Chemical reviews, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 121 papers.

0numbers the graph read from it
0cells of the map it votes in
121citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

121 citing papers in PubMed.

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61 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Advait S NagleGenomics Institute of the Novartis Research Foundation , 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.
Shilpi KhareGenomics Institute of the Novartis Research Foundation , 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.
Arun Babu Kumar
Frantisek SupekGenomics Institute of the Novartis Research Foundation , 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.
Andriy Buchynskyy
Casey J N MathisonGenomics Institute of the Novartis Research Foundation , 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.
Naveen Kumar Chennamaneni
Nagendar Pendem
Frederick S Buckner
Michael H Gelb
Valentina MolteniGenomics Institute of the Novartis Research Foundation , 10675 John Jay Hopkins Drive, San Diego, California 92121, United States.

Funding

Biochemistry of Protein PrenylationR01AI054384 · NIAID · UNIVERSITY OF WASHINGTON · PI BUCKNER, FREDERICK SIMMONS, GELB, MICHAEL H · 2003 to 2012
$5.3M
Rational Development of Anti-Trypanosoma Cruzi DrugsR01AI070218 · NIAID · UNIVERSITY OF WASHINGTON · PI BUCKNER, FREDERICK SIMMONS, GELB, MICHAEL H · 2006 to 2014
$4.4M
Drug Discovery for Human African TrypanosomiasisR01AI106850 · NIAID · UNIVERSITY OF WASHINGTON · PI BUCKNER, FREDERICK SIMMONS, GELB, MICHAEL H · 2013 to 2017
$3.7M
NIAID NIH HHS R01 AI054384NIAID NIH HHS R01 AI070218NIAID NIH HHS R01 AI106850Wellcome Trust
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Drug DesignAntiprotozoal AgentsHumansLeishmaniasisTrypanosomiasisAntiprotozoal Agents

Identifiers

PMID25365529
PMCPMC4633805

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.