Evidence map›Paper›PMID 25364772›Full record

ArticleMolecular therapy. Methods & clinical development2014

Debalina Sarkar, Moanaro Biswas, Gongxian Liao, Howard R Seay, George Q Perrin, David M Markusic, Brad E Hoffman, Todd M Brusko, Cox Terhorst, Roland W Herzog

Open access · goldAbstract read
In one paragraph

Article in Molecular therapy. Methods & clinical development, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 60 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Role of FoxP3Human gene therapy · 2024
    Review
  5. Review
  6. Immunogenicity of Recombinant Adeno-Associated Virus (AAV) Vectors for Gene Transfer.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2023
    Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. CAR- and TRuC-redirected regulatory T cells differ in capacity to control adaptive immunity to FVIII.Molecular therapy : the journal of the American Society of Gene Therapy · 2021
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Debalina SarkarDepartment of Pediatrics, University of Florida, Gainesville, FL 32610, USA.
Moanaro BiswasDepartment of Pediatrics, University of Florida, Gainesville, FL 32610, USA.
Gongxian LiaoDivision of Immunology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston MA 02115. USA.
Howard R SeayDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, FL 32610, USA.
George Q PerrinDepartment of Pediatrics, University of Florida, Gainesville, FL 32610, USA.
David M MarkusicDepartment of Pediatrics, University of Florida, Gainesville, FL 32610, USA.
Brad E HoffmanDepartment of Pediatrics, University of Florida, Gainesville, FL 32610, USA.
Todd M BruskoDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, FL 32610, USA.
Cox TerhorstDivision of Immunology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston MA 02115. USA.
Roland W HerzogDepartment of Pediatrics, University of Florida, Gainesville, FL 32610, USA.
University of Florida · USHarvard University · US

Funding

Vector CoreP01HL078810 · NHLBI · WISTAR INSTITUTE · PI ERTL, HILDEGUND C. J. · 2005 to 2014
$16.7M
Immunology of Factor IX Gene Transfer to LiverR01AI051390 · NIAID · UNIVERSITY OF FLORIDA · PI HERZOG, ROLAND W. · 2002 to 2022
$6.7M
NHLBI NIH HHS P01 HL078810NIAID NIH HHS R01 AI051390
6 · The paper itself

Abstract

Adoptive cell therapy utilizing

Indexed as

AAV vectorcell therapyhemophiliaRegulatory T cellstolerance

Identifiers

PMID25364772
PMCPMC4213815
OpenAlexW2007370376

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.