Evidence map›Paper›PMID 25364628›Full record

ArticleCurrent protocols in mouse biology2012

Mouse Models of Bariatric Surgery.

Deng Ping Yin, Kelli L Boyd, Phillip E Williams, Naji N Abumrad, David H Wasserman

Abstract read
In one paragraph

Article in Current protocols in mouse biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Towards a better mouse model of vertical sleeve gastrectomy.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Deng Ping YinDepartment of Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee, USA ; Department of Mouse Metabolic Phenotyping Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Kelli L BoydDepartment of Pathology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA ; Department of Mouse Metabolic Phenotyping Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Phillip E WilliamsDepartment of Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee, USA ; Department of Diabetes Research Training Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Naji N AbumradDepartment of Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee, USA ; Department of Diabetes Research Training Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
David H WassermanDepartment of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA ; Department of Mouse Metabolic Phenotyping Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA ; Department of Diabetes Research Training Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Vanderbilt University · US

Funding

Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
Vanderbilt Diabetes Research CenterP30DK020593 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ALVIN C POWERS · 2012 to 2026
$29.3M
Vanderbilt Mouse Metabolic Physiology CenterU24DK059637 · NIDDK · VANDERBILT UNIVERSITY · PI WASSERMAN, DAVID H · 2001 to 2015
$14.9M
Role of the Cell Adhesome in Obesity-related Liver DiseasesR01DK050277 · NIDDK · VANDERBILT UNIVERSITY · PI MCGUINNESS, OWEN P · 1995 to 2023
$4.8M
RYGB Improves Metabolism by Interrupting the Gastric Adipose Tissue AxisR01DK091748 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ABUMRAD, NAJI N · 2011 to 2015
$3.0M
NIDDK NIH HHS P30 DK020593NIDDK NIH HHS P30 DK058404NIDDK NIH HHS R01 DK050277NIDDK NIH HHS R01 DK091748NIDDK NIH HHS U24 DK059637
6 · The paper itself

Abstract

Morbid obesity is linked to increased incidences of glucose intolerance, Type 2 diabetes mellitus, cardiovascular diseases, various forms of liver disease, and specific forms of cancer. Treatment of obesity by lifestyle modifications (i.e. changes in diet and exercise) and drug therapy is generally ineffective. Bariatric surgery is currently the most effective means of treating obesity and related disorders. We as well as others have developed surgical procedures for application to genetic mouse models that mimic an array of human bariatric surgical procedures used in the treatment of obesity. The application of bariatric surgery to genetic mouse models will broaden our understanding of the role of the gut in metabolic disease. Models that have been developed include gastric banding, sleeve gastrectomy (SG), Roux-en-Y gastric bypass (RYGB) with a complete exclusion of the stomach, duodenal-jejunal bypass (DJB) and biliopancreatic diversion (BPD). The detailed methods of these procedures are provided.

Indexed as

Bariatric surgerybiliopancreatic diversionduodenal-jejunal bypassgastric bandingmiceRoux-en-Y gastric bypasssleeve gastrectomy

Identifiers

PMID25364628
PMCPMC4214370
OpenAlexW1724009072

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.