ArticleJournal of thoracic disease2014
The role of red blood cell distribution width in mortality and cardiovascular risk among patients with coronary artery diseases: a systematic review and meta-analysis.
Article in Journal of thoracic disease, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 3 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Importance of so called "novel cardiovascular risk factors" in severity of coronary artery calcification; how serious they should be taken: a systematic review and metaanalysis.Archivos de cardiologia de Mexico · 2023Pooled it
- Prognostic value of red cell distribution width in patients undergoing percutaneous coronary intervention: a meta-analysis.BMJ open · 2020Pooled it
- An overall and dose-response meta-analysis of red blood cell distribution width and CVD outcomes.Scientific reports · 2017Pooled it
- Article
- Associations between haemoglobin-to-red cell distribution width ratio and mortality in intracerebral haemorrhage: a population-based analysis of the MIMIC-IV database.Journal of global health · 2026Article
- Elevated Red Blood Cell Distribution Width Predicts Mortality and Major Adverse Cardiovascular Events After Acute Myocardial Infarction: A Large Propensity Score-Matched Cohort Study.Journal of clinical medicine · 2026Article
- Predictors of Long-Term Prognosis Focused on Kidney Function in Patients with Chronic Coronary Syndrome.Diseases (Basel, Switzerland) · 2026Article
- Red blood cell distribution width is associated with coronary artery disease in latent tuberculosis infection: a machine learning-based study.Frontiers in cellular and infection microbiology · 2026Article
- Red cell distribution width as a prognostic indicator in medical and surgical ICU patients.Frontiers in medicine · 2025Article
- Hematological parameters and major adverse cardiovascular events: a prospective study in a Chinese population involving 2,970 participants.International journal of medical sciences · 2025Article
- The importance of the erythrocyte distribution width/albumin ratio in patients with chronic obstructive pulmonary disease exacerbation.Saudi medical journal · 2024Article
- Article
- All-cause and liver-related mortality risk factors in excessive drinkers: Analysis of data from the UK biobank.Alcoholism, clinical and experimental research · 2022Article
- The Emerging Clinical Significance of the Red Cell Distribution Width as a Biomarker in Chronic Obstructive Pulmonary Disease: A Systematic Review.Journal of clinical medicine · 2022Review
- Lymphopenia and mortality among patients undergoing coronary angiography: Long-term follow-up study.Cardiology journal · 2022Article
- Complete Blood Count-Derived Indices as Prognostic Factors of 5-Year Outcomes in Patients With Confirmed Coronary Microvascular Spasm.Frontiers in cardiovascular medicine · 2022Article
- Red Cell Distribution Width and Mortality in Patients Undergoing Percutaneous Coronary Intervention.Biomedicines · 2021Article
- Red Cell Distribution Width and Patient Outcome in Cardiovascular Disease: A ''Real-World'' Analysis.Journal of cardiovascular development and disease · 2021Article
- Role of pre-operative red cell distribution width estimation in the prediction of in-hospital mortality after off-pump coronary artery bypass grafting.Journal of cardiothoracic surgery · 2021Article
- Red Blood Cell Distribution Width, Disease Severity, and Mortality in Hospitalized Patients with SARS-CoV-2 Infection: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2021Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRed cell distribution width (RDW) might be a novel biomarker that reflects multiple physiological impairments related to atherosclerosis and coronary artery diseases (CAD). We conducted this systematic review and meta-analysis to evaluate the association of RDW between all-cause mortality and fatal/non-fatal cardiovascular disease (CVD) events in CAD patients.
methodsRelevant studies were searched and identified in the MEDLINE and EMBASE databases. English-language prospective studies that reported risk estimates for RDW and mortality/CVD events were included. Data were extracted regarding the characteristics and clinical outcomes, and a quality assessment was conducted. Results were extracted for the highest versus lowest RDW level, and meta-analyses were carried out using random effects models.
resultsWe identified 22 studies enrolling 80,216 participants. The study duration ranged between 1 month and 23 years. Of the 15 studies that were included in the meta-analysis, higher RDW indicated a significant increased risk for all-cause mortality in CAD patients: pooled risk ratio (RR) 2.20 (95% CI, 1.42-3.39; P<0.0004). The results for fatal, non-fatal and fatal/non-fatal events were: pooled RR 1.80 (95% CI, 1.35-2.41; P<0.0001), RR 1.86 (95% CI, 1.50-2.31; P<0.00001) and RR 2.13 (95% CI, 1.20-3.77; P=0.01). Heterogeneity was moderately present; however, sensitivity analyses for follow-up duration, CAD subtype, or RDW as dichotomous values showed similar results.
conclusionsThe meta-analysis indicates that higher RDW levels are associated with increased risk of mortality and CVD events in patients with established CAD.
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