Evidence map›Paper›PMID 25364301›Full record

ArticleBMC anesthesiology2014

Improving diagnostic accuracy in assessing pulmonary edema on bedside chest radiographs using a standardized scoring approach.

Matthias Hammon, Peter Dankerl, Heinz Leonhard Voit-Höhne, Martin Sandmair, Ferdinand Josef Kammerer, Michael Uder, Rolf Janka

Open access · goldAbstract read
In one paragraph

Article in BMC anesthesiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Deep Learning to Quantify Pulmonary Edema in Chest Radiographs.Radiology. Artificial intelligence · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Matthias HammonDepartment of Radiology, University Hospital Erlangen, Maximiliansplatz 1, 91054 Erlangen, Germany.
Peter DankerlDepartment of Radiology, University Hospital Erlangen, Maximiliansplatz 1, 91054 Erlangen, Germany.
Heinz Leonhard Voit-HöhneDepartment of Radiology, Hospital Ansbach, Escherichstrasse 1, 91522 Ansbach, Germany.
Martin SandmairDepartment of Radiology, University Hospital Erlangen, Maximiliansplatz 1, 91054 Erlangen, Germany.
Ferdinand Josef KammererDepartment of Radiology, University Hospital Erlangen, Maximiliansplatz 1, 91054 Erlangen, Germany.
Michael UderDepartment of Radiology, University Hospital Erlangen, Maximiliansplatz 1, 91054 Erlangen, Germany.
Rolf JankaDepartment of Radiology, University Hospital Erlangen, Maximiliansplatz 1, 91054 Erlangen, Germany.
Universitätsklinikum Erlangen · DEAnsbach University of Applied Sciences · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo assess the value of a score-based system which allows standardized evaluation of pulmonary edema on bedside chest radiographs (CXRs) under routine clinical conditions.

methodsSeven experienced readers assessed bedside CXRs of ten patients with an extravascular lung water (EVLW)-value of ≤ 8 mL/kg (range: 4-8 mL/kg; indicates no pulmonary edema) and a series of ten patients with an EVLW-value of ≥ 15 mL/kg (range: 15-21 mL/kg; = indicates a pulmonary edema) with and without customized software which would permit a standardized assessment of the various indications of pulmonary edema. The software provides a score that identifies patients with and without pulmonary edema. EVLW-values were measured instantly after bedside CXR imaging using a pulse contour cardiac output (PiCCO) system and served as a reference standard. The patients were non-traumatic and not treated with diuretics or dobutamine during bedside CXR imaging and the PiCCO measurements. Mean sensitivity, specificity, positive and negative predictive value, the percentage of overall agreement and the free-marginal multirater kappa value was calculated for both the standard and the standardized score-based approach. The net reclassification index was calculated for each reader as well as for all readers.

resultsEvaluation of bedside CXRs by means of the score-based approach took longer (23 ± 12 seconds versus 7 ± 3 seconds without the use of the software) but improved radiologists' sensitivity (from 57 to 77%), specificity (from 90 to 100%) and the free-marginal multirater kappa value (from 0.34 to 0.68). The positive predictive value was raised from 85 to 100% and the negative predictive value from 68 to 81%. A net reclassification index of 0.3 (all readers) demonstrates an improvement in prediction performance gained by the score-based approach. The percentage of overall agreement was 67% with the standard approach and 84% with the software-based approach.

conclusionsThe diagnostic accuracy of bedside CXRs to discriminate patients with elevated EVLW-values from those with a normal value can be improved with the use of a standardized score-based approach. The investigated system is freely available as a web-based application (accessible via: http://www.radiologie.uk-erlangen.de/aerzte-und-zuweiser/edema).

Indexed as

AdultAgedAged, 80 and overCardiac OutputExtravascular Lung WaterFemaleHumansImage Processing, Computer-AssistedMaleMiddle AgedPoint-of-Care SystemsPulmonary EdemaRadiography, ThoracicReference StandardsReproducibility of ResultsSoftwareBedside chest radiographExtravascular lung water (EVLW)Pulmonary edemaScoring systemWeb-based application

Identifiers

PMID25364301
PMCPMC4216356
OpenAlexW1965400835

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.