Evidence map›Paper›PMID 25364239›Full record

ArticleClinical interventions in aging2014

Use of basal insulin and the associated clinical outcomes among elderly nursing home residents with type 2 diabetes mellitus: a retrospective chart review study.

Keith L Davis, Wenhui Wei, Juliana L Meyers, Brett S Kilpatrick, Naushira Pandya

Open access · goldAbstract read
In one paragraph

Article in Clinical interventions in aging, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Sliding Scale Insulin Use in Nursing Homes Before and After Onset of the COVID-19 Pandemic.Journal of the American Medical Directors Association · 2024
    Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Keith L DavisRTI Health Solutions, Research Triangle Park, NC, USA.
Wenhui WeiSanofi US, Inc, Bridgewater, NJ, USA.
Juliana L MeyersRTI Health Solutions, Research Triangle Park, NC, USA.
Brett S KilpatrickAnalytiCare, LLC, Glenview, IL, USA.
Naushira PandyaNova Southeastern University College of Osteopathic Medicine, Fort Lauderdale, FL, USA.
RTI Health Solutions · USNova Southeastern University · USSanofi (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe management of type 2 diabetes mellitus in long-term care (LTC) settings can be complex as a result of age-related complications. Despite guideline recommendations, sliding scale insulin remains commonplace in the LTC setting and data on basal insulin use are lacking.

methodsThis retrospective study used medical chart data and the Minimum Data Set from elderly LTC facility patients who received basal insulin (insulin glargine, insulin detemir, or neutral protamine Hagedorn insulin) for the treatment of diabetes, to investigate the practice patterns and associated clinical outcomes.

resultsA total of 2,096 elderly, insulin-treated patients in LTC were identified, with 59.5% of them (N=1,247) receiving basal insulin. Of these, more than 50% of patients received sliding scale insulin in co-administration with basal insulin. Despite its ease of use, insulin pen use was very low, at 14.6%. Significant differences were observed between the basal insulin groups for glycated hemoglobin level and dosing frequency. Hypoglycemia was uncommon -17.2% of patients experienced at least one event, and there was no significant difference in the prevalence of hypoglycemia between the groups.

conclusionThese data suggest the underutilization of basal insulin in the LTC setting and worryingly high combinational use with sliding scale insulin. Differences in glycated hemoglobin and dosing frequencies between types of basal insulin warrant further comparative effectiveness studies.

Indexed as

Homes for the AgedNursing HomesAgedAged, 80 and overCross-Sectional StudiesDiabetes Mellitus, Type 2Drug Therapy, CombinationDrug UtilizationFemaleGlycated HemoglobinHumansHypoglycemiaInjections, SubcutaneousInsulin DetemirInsulin GlargineInsulin, IsophaneGlycated Hemoglobinhemoglobin A1c protein, humanInsulin DetemirInsulin GlargineInsulin, IsophaneInsulin, Long-Actinginsulin detemirinsulin glarginelong-term careNPH insulinnursing homestype 2 diabetes mellitus

Identifiers

PMID25364239
PMCPMC4211864
OpenAlexW2160714661

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.