Evidence map›Paper›PMID 25363807›Full record

ArticleZoonoses and public health2015

Human Brucella canis Infection and Subsequent Laboratory Exposures Associated with a Puppy, New York City, 2012.

C M Dentinger, K Jacob, L V Lee, H A Mendez, K Chotikanatis, P L McDonough, D M Chico, B K De, R V Tiller, R M Traxler and 4 more

Abstract readCase Reports
In one paragraph

Article in Zoonoses and public health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. One health (Amsterdam, Netherlands) · 2026
    Review
  2. Pathogens (Basel, Switzerland) · 2026
    Review
  3. Article
  4. Article
  5. A Family Cluster of Imported HumanTropical medicine and infectious disease · 2025
    Article
  6. Brucellosis in humans caused byThe Canadian veterinary journal = La revue veterinaire canadienne · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. The emergence ofEmerging microbes & infections · 2023
    Review
  11. Article
  12. Frontiers in veterinary science · 2023
    Article
  13. Article
  14. Article
  15. Canine brucellosis in three littermates, case report.Frontiers in veterinary science · 2022
    Article
  16. Article
  17. Tracking the Distribution ofMicroorganisms · 2021
    Article
  18. Review
  19. Seroprevalence of Brucella canis in canines from a dog shelter in Bogotá, ColombiaBiomedica : revista del Instituto Nacional de Salud · 2021
    Article
  20. Canine Brucellosis: An Update.Frontiers in veterinary science · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

C M DentingerNew York City Department of Health and Mental Hygiene, New York City, NY, USA.
K JacobDownstate Medical Center, State University of New York, Brooklyn, NY, USA.
L V LeeNew York City Department of Health and Mental Hygiene, New York City, NY, USA.
H A MendezDownstate Medical Center, State University of New York, Brooklyn, NY, USA.
K ChotikanatisDownstate Medical Center, State University of New York, Brooklyn, NY, USA.
P L McDonoughCornell University, New York State College of Veterinary Medicine, Ithaca, NY, USA.
D M ChicoNew York State Department of Agriculture and Markets, Albany, NY, USA.
B K DeCenters for Disease Control and Prevention, National Center for Emerging and Zoonotic Disease, Atlanta, GA, USA.
R V TillerCenters for Disease Control and Prevention, National Center for Emerging and Zoonotic Disease, Atlanta, GA, USA.
R M TraxlerCenters for Disease Control and Prevention, National Center for Emerging and Zoonotic Disease, Atlanta, GA, USA.
E R CampagnoloCenters for Disease Control and Prevention, Office of Public Health Preparedness and Response, Office of Science and Public Health Practice, Atlanta, GA, USA.
D SchmittIowa Department of Agriculture and Land Stewardship, Des Moines, IA, USA.
M A GuerraCenters for Disease Control and Prevention, National Center for Emerging and Zoonotic Disease, Atlanta, GA, USA.
S A SlavinskiNew York City Department of Health and Mental Hygiene, New York City, NY, USA.

Funding

The Affordable Care Act: Building Epidemiology, Laboratory-MCV/PCVU50CI000899 · CI · NEW YORK CITY HEALTH/MENTAL HYGIENE · PI LAYTON, MARCELLE CAROL · 2010 to 2013
$7.4M
Intramural CDC HHS CC999999NCPDCID CDC HHS U50 CI000899OPHPR CDC HHS 5U90TP000546OPHPR CDC HHS U90 TP000546
6 · The paper itself

Abstract

Human Brucella canis infection incidence is unknown. Most identified cases are associated with pet dogs. Laboratory-acquired infections can occur following contact with Brucella spp. We identified a paediatric B. canis case, the source and other exposed persons. A 3-year-old New York City child with fever and dyspnoea was hospitalized for 48 h for bronchiolitis. After her admission, blood culture grew B. canis, she was prescribed anti-microbials and recovered. B. canis was also isolated from blood of the child's pet dog; these isolates were genetically similar. The dog originated from an Iowa breeding facility which was quarantined after identification of the dog's infection. Additionally, 31 laboratory workers were exposed and subsequently monitored for symptoms; 15 completed post-exposure prophylaxis. To our knowledge, this is the first report strongly suggesting B. canis zoonotic transmission to a child in the United States, and highlights the need for coordinated control policies to minimize human illness.

Indexed as

AnimalsAnti-Bacterial AgentsBrucella canisBrucellosisChild, PreschoolCommerceDog DiseasesDogsFemaleHumansIowaNew York CityPennsylvaniaTrimethoprim, Sulfamethoxazole Drug CombinationZoonosesAnti-Bacterial AgentsTrimethoprim, Sulfamethoxazole Drug CombinationBrucella canisBrucella infectionbrucellosiscanine brucellosislaboratory exposurepersonal protectionpet breederspet dogsveterinary treatmentzoonosis

Identifiers

PMID25363807
PMCPMC4639931

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.