Evidence map›Paper›PMID 25363261›Full record

ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2014

Intra-operative vertebroplasty combined with posterior cord decompression. A report of twelve cases.

Luca Allegretti, Nicola Mavilio, Pietro Fiaschi, Roberto Bragazzi, Mattia Pacetti, Lara Castelletti, Laura Saitta, Lucio Castellan

Open access · greenAbstract read
In one paragraph

Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Clinical Applications of Injectable Biomaterials.Advances in experimental medicine and biology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Luca AllegrettiDepartment of Neuroradiology, San Martino Hospital; Genoa, Italy - pietro.fiaschi@me.com.
Nicola MavilioDepartment of Neuroradiology, San Martino Hospital; Genoa, Italy.
Pietro FiaschiDepartment of Neurosurgery, San Martino Hospital; Genoa, Italy.
Roberto BragazziDepartment of Neurosurgery, San Martino Hospital; Genoa, Italy.
Mattia PacettiDepartment of Neurosurgery, San Martino Hospital; Genoa, Italy.
Lara CastellettiDepartment of Neuroradiology, San Martino Hospital; Genoa, Italy.
Laura SaittaDepartment of Neuroradiology, San Martino Hospital; Genoa, Italy.
Lucio CastellanDepartment of Neuroradiology, San Martino Hospital; Genoa, Italy.
Ospedale Policlinico San Martino · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Percutaneous vertebroplasty (VP) is a minimally invasive technique for the treatment of vertebral pathology providing early vertebral stabilization and pain relief. In cases of vertebral pathology complicated by spinal cord compression with associated neurological deficits, VP alone cannot be performed free of risks. We describe a combined approach in which decompressive laminectomy and intra-operative vertebroplasty (IVP) are performed during a single session. Among the 252 VP performed in our centre in the past three years, 12 patients (12 vertebral levels) with different pathologies (six symptomatic haemangiomas, two metastatic fractures, four osteoporotic fractures) were treated with an open procedure combined with surgery. All cases were treated with decompressive laminectomy and IVP (mono/bipeduncular or median-posterior trans-somatic access). Five patients with symptomatic haemangiomas were treated with endovascular embolization prior to the combined approach. A visual analogue scale (VAS) was applied to assess pain intensity before and after surgery. The neurological deficits were evaluated with an ASIA impairment scale. In all cases benefit from pain and neurological deficits was observed. The mean VAS score decreased from 7.8 to 2.5 after surgery. The ASIA score improved in all cases (five cases from D to E and five cases from C to D). No clinical complications were observed. In one case a CT scan performed after the procedure showed a foraminal accumulation of PMMA, but the patient referred no symptoms. IVP can be successfully applied in different pathologies affecting the vertebrae. In our limited series this approach proved safe and efficient to provide decompression of spinal cord and dural sac and vertebral body stabilization in a single session.

Indexed as

AdultAgedCombined Modality TherapyDecompression, SurgicalEmbolization, TherapeuticFemaleHemangiomaHumansLaminectomyMagnetic Resonance ImagingMaleMiddle AgedNervous System DiseasesOsteoporosisPain MeasurementSpinal Cord Compressionembolizationfluoroscopyintra-operative vertebroplastylaminectomyPMMA

Identifiers

PMID25363261
PMCPMC4243228
OpenAlexW2161580316

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.