ArticleHPB : the official journal of the International Hepato Pancreato Biliary Association2015
Mortality after a cholecystectomy: a population-based study.
Article in HPB : the official journal of the International Hepato Pancreato Biliary Association, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 3 of them syntheses that pooled it.
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Who cites it
45 citing papers in PubMed, 3 syntheses or guidelines pooled it, 100 citations in OpenAlex.
- Comparison of laparoscopic cholecystectomy in children at paediatric centres and adult centres: a systematic review and meta-analysis.Annals of the Royal College of Surgeons of England · 2025Pooled it
- Should Procalcitonin Be Included in Acute Cholecystitis Guidelines? A Systematic Review.Medicina (Kaunas, Lithuania) · 2023Pooled it
- Three-port versus four-port technique for laparoscopic cholecystectomy: systematic review and meta-analysis.BJS open · 2022Pooled it
- Post-Operative Safety Outcomes and 5-Year Healthcare Utilisation After Bariatric Surgery vs. Other Elective Types of Surgical Treatments - A Retrospective Observational Cohort Study.Obesity surgery · 2026Observational
- Article
- Protocol for the development of a procedure guide on Laparoscopic Cholecystectomy: Beyond bile duct injury prevention.PloS one · 2026Article
- Mortality and cardiovascular disease after cholecystectomy in type 2 diabetes: A nationwide longitudinal cohort study.Journal of hepato-biliary-pancreatic sciences · 2025Article
- Surgical risk calculator development for postoperative outcomes after laparoscopic cholecystectomy: a multicenter prospective cohort study.Annals of surgical treatment and research · 2025Article
- 30-day Morbidity and Mortality after Cholecystectomy for Benign Gallbladder Disease (AMBROSE): A Prospective, International Collaborative Cohort Study.Annals of surgery · 2025Observational
- Hepatic steatosis mediates the relationship between cholecystectomy and BMI increase: a population-based study.Frontiers in medicine · 2025Article
- Day case laparoscopic cholecystectomy: a review of patient selection factors and identification of potential barriers to same-day discharge.ANZ journal of surgery · 2024Review
- Plain Computed Tomography for Differentiating Neoplastic and Non-neoplastic Pedunculated Gallbladder Polyps.Internal medicine (Tokyo, Japan) · 2024Article
- New models for prediction of postoperative pulmonary complications in lung resection candidates.ERJ open research · 2024Article
- Endoscopic Gallbladder Drainage: A Comprehensive Review on Indications, Techniques, and Future Perspectives.Medicina (Kaunas, Lithuania) · 2024Review
- Safety and cost of performing laparoscopic sleeve gastrectomy with same day discharge at a large academic hospital.Surgical endoscopy · 2024Article
- Safety and safety protocols for living donor nephrectomy in Italy.Updates in surgery · 2024Article
- Propensity score-matched comparison of safety outcomes between high-risk and low-risk patients towards early hospital discharge after laparoscopic cholecystectomy.Annals of medicine and surgery (2012) · 2023Article
- Comprehensive assessment of the management of acute cholecystitis in Scotland: population-wide cohort study.BJS open · 2023Article
- Evaluation of 30-day morbidity and mortality of laparoscopic cholecystectomy: a multicenter prospective observational Indian Association of Gastrointestinal Endoscopic Surgeons (IAGES) Study.Surgical endoscopy · 2023Observational
- The risk of post-operative pulmonary complications in lung resection candidates with normal forced expiratory volume in 1 s and diffusing capacity of the lung for carbon monoxide: a prospective multicentre study.ERJ open research · 2023Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe trade-off between the benefits of surgery for gallstone disease for a large population and the risk of lethal outcome in a small minority requires knowledge of the overall mortality.
methodsBetween 2007 and 2010, 47 912 cholecystectomies for gallstone disease were registered in the Swedish Register for Cholecystectomy and endoscopic retrograde cholangiopancreatography (ERCP) (GallRiks). By linkage to the Swedish Death Register, the 30-day mortality after surgery was determined. The age- and sex-standardized mortality ratio (SMR) was estimated by dividing the observed mortality with the expected mortality rate in the Swedish general population 2007. The Charlson Comorbidity Index (CCI) was estimated by International Classification of Diseases (ICD) codes retrieved from the National Patient Register.
resultsWithin 30 days after surgery, 72 (0.15%) patients died. The 30-day mortality was close [SMR = 2.58; 95% confidence interval (CI): 2.02-3.25] to that of the Swedish general population. In multivariable logistic regression analysis, predictors of 30-day mortality were age >70 years [odds ratio (OR) 7.04, CI: 2.23-22.26], CCI > 2 (OR 1.93, CI: 1.06-3.51), American Society of Anesthesiologists (ASA) > 2 (OR 13.28, CI: 4.64-38.02), acute surgery (OR 10.05, CI:2.41-41.95), open surgical approach (OR 2.20, CI: 1.55-4.69) and peri-operative complications (OR 3.27, CI: 1.74-6.15). DISCUSSION: Mortality after cholecystectomy is low. Co-morbidity and peri-operative complications may, however, increase mortality substantially. The increased mortality risk associated with open cholecystectomy could be explained by confounding factors influencing the decision to perform open surgery.
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