Evidence map›Paper›PMID 25363056›Full record

ArticleSouth African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde2014

Comparability of total cardiovascular disease risk estimates using laboratory and non-laboratory based assessments in urban-dwelling South Africans: the CRIBSA study.

Nasheeta Peer, Carl Lombard, Krisela Steyn, Thomas Gaziano, Naomi Levitt

Open access · goldAbstract readComparative Study
In one paragraph

Article in South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Nasheeta PeerNon-communicable Diseases Research Unit, Medical Research Council, Durban, South Africa. nasheeta.peer@mrc.ac.za.
Carl Lombard
Krisela Steyn
Thomas Gaziano
Naomi Levitt
South African Medical Research Council · ZAHarvard University · USSouth African Tuberculosis Vaccine Initiative · ZAUniversity of Cape Town · ZA

Funding

Global Cardiovascular Disease Policy Model for Screening Prevention and TreatmentR01HL104284 · NHLBI · HARVARD SCHOOL OF PUBLIC HEALTH · PI GAZIANO, THOMAS A · 2010 to 2014
$2.5M
NHLBI NIH HHS R01 HL104284
6 · The paper itself

Abstract

objectivesTo establish the prevalence and determinants of the 10-year risk of a cardiovascular disease (CVD) event in 25 - 74-year-old black Africans in Cape Town, South Africa, using Framingham laboratory- and non-laboratory-based and National Health and Nutrition Examination Survey (NHANES) I non-laboratory-based equations.

methodsCVD risk factors were determined by questionnaires, clinical measurements and biochemical analyses. Survey logistic regression analyses assessed the sociodemographic determinants of CVD risk ≥20%.

resultsThere were 1 025 participants, 369 men and 656 women. Mean 10-year risk for a CVD event by Framingham laboratory- and non-laboratory-based and NHANES I non-laboratory-based equations for men was 9.0% (95% confidence interval 7.7 - 10.3), 11.1% (9.6 - 12.6) and 9.0% (7.6 - 10.3), and for women 5.4% (4.7 - 6.1), 6.8% (5.9 - 7.7) and 8.7% (7.6 - 9.8). Correlations between laboratory- and non-laboratory-based scores were high (0.915 - 0.963). The prevalence of laboratory-based CVD risk ≥20% was 13.0% in men and 6.1% in women. In the logistic model for men, ≤7 years of education (odds ratio 3.09; 95% CI 1.67 - 5.71) and being unemployed (3.44; 1.21 - 9.81) compared with employed were associated with laboratory-based high risk. In women, high risk was associated with ≤7 years of education (4.20; 1.96 - 9.01), living in formal v. informal housing (2.74; 1.24 - 6.06) and being poor (middle v. lowest tertile 0.29; 0.13 - 0.66). In the Framingham non-laboratory-based logistic models there were no changes in the direction or significance of the variables except for housing, which was no longer significant in women.

conclusionsComparability of laboratory- and non-laboratory-based CVD risk estimates illustrates the utility of the latter in resource-constrained settings.

Indexed as

Cardiovascular DiseasesDiabetes Mellitus, Type 2DyslipidemiasHypertensionOverweightSmokingAdultAgedClinical Laboratory TechniquesFemaleHumansLogistic ModelsMaleMiddle AgedNutrition SurveysOdds Ratio

Identifiers

PMID25363056
PMCPMC4816643
OpenAlexW2154716280

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.