ArticleApplied and environmental microbiology2015
rpoS-Regulated core genes involved in the competitive fitness of Salmonella enterica Serovar Kentucky in the intestines of chickens.
Article in Applied and environmental microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 37 citations in OpenAlex.
- Whole genome-sequence-based molecular characterisation of Salmonella Kentucky co-resistant to fluoroquinolones and cephalosporins isolated from children during 2017 to 2024: emergence of blaBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026Article
- A commercial bacteriophage cocktail failed to decolonize Zophobas morio larvae and promoted overgrowth of an OXA-48-producing Salmonella enterica.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Article
- Investigating the differences inFrontiers in veterinary science · 2026Article
- Whole-genome sequencing and phylogenetic analysis ofMicrobiology spectrum · 2025Article
- Longitudinal study highlights patterns ofFrontiers in microbiology · 2025Article
- Peeling back the many layers of competitive exclusion.Frontiers in microbiology · 2024Article
- Genomic and phenotypic characterization ofMicrobial genomics · 2023Article
- Combined Quantification and Deep Serotyping for Salmonella Risk Profiling in Broiler Flocks.Applied and environmental microbiology · 2023Article
- The Use of Star Anise-Cinnamon Essential Oil as an Alternative Antibiotic in Prevention ofAntibiotics (Basel, Switzerland) · 2022Article
- RegionalApplied and environmental microbiology · 2022Article
- Genomic characterization of multidrug-resistantMicrobial genomics · 2022Article
- Bacterial composition of a competitive exclusion product and its correlation with product efficacy at reducingFrontiers in physiology · 2022Article
- Whole-Genome Sequencing Provides Insight Into Antimicrobial Resistance and Molecular Characteristics ofFrontiers in microbiology · 2022Article
- Salmonella Genomics in Public Health and Food Safety.EcoSal Plus · 2021Article
- Competitive Exclusion of Intra-GenusMicroorganisms · 2021Article
- Strength Lies in Diversity: How Community Diversity LimitsFrontiers in microbiology · 2021Article
- Iron-Uptake Systems of Chicken-AssociatedMicroorganisms · 2020Review
- Salmonella enterica subsp.Applied and environmental microbiology · 2019Article
- Embracing Diversity: Differences in Virulence Mechanisms, Disease Severity, and Host Adaptations Contribute to the Success of NontyphoidalFrontiers in microbiology · 2019Review
- Phenotypic Prediction: LinkingFrontiers in microbiology · 2018Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
Abstract
Salmonella enterica serovar Kentucky has become the most frequently isolated serovar from poultry in the United States over the past decade. Despite its prevalence in poultry, it causes few human illnesses in the United States. The dominance of S. Kentucky in poultry does not appear to be due to single introduction of a clonal strain, and its reduced virulence appears to correlate with the absence of virulence genes grvA, sseI, sopE, and sodC1. S. Kentucky's prevalence in poultry is possibly attributable to its metabolic adaptation to the chicken cecum. While there were no difference in the growth rate of S. Kentucky and S. Typhimurium grown microaerophilically in cecal contents, S. Kentucky persisted longer when chickens were coinfected with S. Typhimurium. The in vivo advantage that S. Kentucky has over S. Typhimurium appears to be due to differential regulation of core Salmonella genes via the stationary-phase sigma factor rpoS. Microarray analysis of Salmonella grown in cecal contents in vitro identified several metabolic genes and motility and adherence genes that are differentially activated in S. Kentucky. The contributions of four of these operons (mgl, prp, nar, and csg) to Salmonella colonization in chickens were assessed. Deletion of mgl and csg reduced S. Kentucky persistence in competition studies in chickens infected with wild-type or mutant strains. Subtle mutations affecting differential regulation of core Salmonella genes appear to be important in Salmonella's adaptation to its animal host and especially for S. Kentucky's emergence as the dominant serovar in poultry.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.