Evidence map›Paper›PMID 25361841›Full record

Trial reportBMJ open2014

Computerised cognitive behaviour therapy for depression in adolescents: study protocol for a feasibility randomised controlled trial.

Barry Wright, Lucy Tindall, Elizabeth Littlewood, Joy Adamson, Victoria Allgar, Sophie Bennett, Simon Gilbody, Chrissie Verduyn, Ben Alderson-Day, Lisa Dyson and 2 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMJ open, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Review
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Barry WrightLimetrees Child Adolescent and Family Unit, York, UK.
Lucy TindallLimetrees Child Adolescent and Family Unit, York, UK.
Elizabeth LittlewoodThe University of York, York, UK.
Joy AdamsonThe University of York, York, UK.
Victoria AllgarThe University of York, York, UK.
Sophie BennettLimetrees Child Adolescent and Family Unit, York, UK.
Simon GilbodyThe University of York, York, UK.
Chrissie VerduynManchester Children's Hospital NHS Trust, Manchester, UK.
Ben Alderson-DayLimetrees Child Adolescent and Family Unit, York, UK.
Lisa DysonThe University of York, York, UK.
Dominic TrépelThe University of York, York, UK.
Shehzad AliThe University of York, York, UK.
University of York · GBRoyal Manchester Children's Hospital · GB

Funding

Department of Health PB-PG-0609-19295
6 · The paper itself

Abstract

introductionThe 1 year prevalence of depression in adolescents is about 2%. Treatment with antidepressant medication is not recommended for initial treatment in young people due to concerns over high side effects, poor efficacy and addictive potential. Evidence suggests that cognitive behaviour therapy (CBT) is an effective treatment for depression and is currently one of the main treatment options recommended in adolescents. Given the affinity young people have with information technology they may be treated effectively, more widely and earlier in their illness evolution using computer-administered CBT (CCBT). Currently little is known about the clinical and resource implications of implementing CCBT within the National Health Service for adolescents with low mood/depression. We aim to establish the feasibility of running a fully powered randomised controlled trial (RCT). METHODS AND ANALYSIS: Adolescents aged 12-18 with low mood/depression, (scoring ≥20 on the Mood and Feelings Questionnaire (MFQ)), will be approached to participate. Consenting participants will be randomised to either a CCBT programme (Stressbusters) or accessing selected websites providing information about low mood/depression. The primary outcome measure will be the Beck Depression Inventory (BDI). Participants will also complete generic health measures (EQ5D-Y, HUI2) and resource use questionnaires to examine the feasibility of cost-effectiveness analysis. Questionnaires will be completed at baseline, 4 and 12-month follow-ups. Progress and risk will be monitored via the MFQ administered at each treatment session. The acceptability of a CCBT programme to adolescents; and the willingness of clinicians to recruit participants and of participants to be randomised, recruitment rates, attrition rates and questionnaire completion rates will be collected for feasibility analysis. We will estimate 'numbers needed' to plan a fully powered RCT of clinical and cost-effectiveness. ETHICS AND DISSEMINATION: The current trial protocol received a favourable ethical opinion from Leeds (West) Research and Ethics Committee. (Reference: 10/H1307/137). TRIAL REGISTRATION NUMBER: ISRCTN31219579.

Indexed as

AdolescentChildCognitive Behavioral TherapyDepressionDepressive DisorderFeasibility StudiesHumansPatient Acceptance of Health CareTherapy, Computer-AssistedMENTAL HEALTH

Identifiers

PMID25361841
PMCPMC4216856
OpenAlexW2160617014

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.