Evidence map›Paper›PMID 25361723›Full record

ArticleGlobal health action2014

Hypertension: adherence to treatment in rural Bangladesh--findings from a population-based study.

Masuma Akter Khanam, Wietze Lindeboom, Tracey Lynn Perez Koehlmoos, Dewan Shamsul Alam, Louis Niessen, Abul Hasnat Milton

Open access · goldAbstract read
In one paragraph

Article in Global health action, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 2 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 2 syntheses or guidelines pooled it, 80 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Observational
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 4 countries.

Masuma Akter KhanamCentre for Control of Chronic Diseases in Bangladesh, icddr,b, Mohakali, Bangladesh; Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health, Faculty of Health and Medicine, The University of Newcastle, Callaghan, NSW, Australia.
Wietze LindeboomCentre for Control of Chronic Diseases in Bangladesh, icddr,b, Mohakali, Bangladesh.
Tracey Lynn Perez KoehlmoosCentre for Control of Chronic Diseases in Bangladesh, icddr,b, Mohakali, Bangladesh.
Dewan Shamsul AlamCentre for Control of Chronic Diseases in Bangladesh, icddr,b, Mohakali, Bangladesh.
Louis NiessenHealth Economics, Liverpool School of Tropical Medicine, Liverpool, UK; International Health, Johns Hopkins School of Public Health, Baltimore, MD, USA.
Abul Hasnat MiltonCentre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health, Faculty of Health and Medicine, The University of Newcastle, Callaghan, NSW, Australia; milton.hasnat@newcastle.edu.au.
International Centre for Diarrhoeal Disease Research · BDUniversity of Baltimore · USUniversity of Newcastle Australia · AU

Funding

Fogarty International Clinical Research Scholars Support Center @ Vanderbilt-AAMCR24TW007988 · FIC · VANDERBILT UNIVERSITY · PI VERMUND, STEN H. · 2007 to 2011
$27.6M
FIC NIH HHS R24 TW007988
6 · The paper itself

Abstract

backgroundPoor adherence has been identified as the main cause of failure to control hypertension. Poor adherence to antihypertensive treatment is a significant cardiovascular risk factor, which often remains unrecognized. There are no previous studies that examined adherence with antihypertensive medication or the characteristics of the non-adherent patients in Bangladesh.

objectiveThis paper aims to describe hypertension and factors affecting adherence to treatment among hypertensive persons in rural Bangladesh.

designThe study population included 29,960 men and women aged 25 years and older from three rural demographic surveillance sites of the International Center for Diarrheal Disease Research, Bangladesh (icddr,b): Matlab, Abhoynagar, and Mirsarai. Data was collected by a cross-sectional design on diagnostic provider, initial, and current treatment. Discontinuation of medication at the time of interview was defined as non-adherence to treatment.

resultsThe prevalence of hypertension was 13.67%. Qualified providers diagnosed only 53.5% of the hypertension (MBBS doctors 46.1 and specialized doctors 7.4%). Among the unqualified providers, village doctors diagnosed 40.7%, and others (nurse, health worker, paramedic, homeopath, spiritual healer, and pharmacy man) each diagnosed less than 5%. Of those who started treatment upon being diagnosed with hypertension, 26% discontinued the use of medication. Age, sex, education, wealth, and type of provider were independently associated with non-adherence to medication. More men discontinued the treatment than women (odds ratio [OR] 1.74, confidence interval [CI] 1.48-2.04). Non-adherence was greater when hypertension was diagnosed by unqualified providers (OR 1.52, CI 1.31-1.77). Hypertensive patients of older age, least poor quintile, and higher education were less likely to be non-adherent. Patients with cardiovascular comorbidity were also less likely to be non-adherent to antihypertensive medication (OR 0.79, CI 0.64-0.97).

conclusionsAlthough village doctors diagnose 40% of hypertension, their treatments are associated with a higher rate of non-adherence to medication. The hypertension care practices of the village doctors should be explored by additional research. More emphasis should be placed on men, young people, and people with low education. Health programs focused on education regarding the importance of taking continuous antihypertensive medication is now of utmost importance.

Indexed as

Medication AdherenceAdultAntihypertensive AgentsBangladeshCross-Sectional StudiesFemaleHumansHypertensionInterviews as TopicMaleMiddle AgedPopulation SurveillancePrevalenceRisk FactorsRural PopulationSex FactorsAntihypertensive Agentsadherence to treatmentBangladeshhypertensionlow-income countryvillage doctors

Identifiers

PMID25361723
PMCPMC4212079
OpenAlexW2111774852

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.