Treating HSV and CMV reactivations in critically ill patients who are not immunocompromised: pro.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

1. Effect of antiviral therapy on the outcomes of mechanically ventilated patients with herpes simplex virus detected in the respiratory tract: a systematic review and meta-analysis.Critical care (London, England) · 2020
   Pooled it
2. Acyclovir for Mechanically Ventilated Patients With Herpes Simplex Virus Oropharyngeal Reactivation: A Randomized Clinical Trial.JAMA internal medicine · 2020
   Trial
3. Higher prevalence of cytomegalovirus and Epstein-Barr virus in acute-on-chronic liver failure.JHEP reports : innovation in hepatology · 2026
   Article
4. Herpes simplex virus 1 encodes a STING antagonist that can be therapeutically targeted.Cell reports. Medicine · 2025
   Article
5. Surviving Sepsis Campaign: Research Opportunities for Infection and Blood Purification Therapies.Critical care explorations · 2021
   Review
6. Impact of antiviral treatment on long-term prognosis in non-immunocompromised patients with CMV reactivation.BMC infectious diseases · 2021
   Article
7. Update in Viral Infections in the Intensive Care Unit.Frontiers in medicine · 2021
   Review
8. Correction to: The role of high load herpes simplex virus in patients with mechanical ventilation: a real hospital acquired viral lung infection needs antiviral therapy?Critical care (London, England) · 2020
   Article
9. The role of high load herpes simplex virus in patients with mechanical ventilation: a real hospital acquired viral lung infection needs antiviral therapy?Critical care (London, England) · 2020
   Article
10. Respiratory viruses in mechanically ventilated patients: a pilot study.BMC pulmonary medicine · 2020
    Observational
11. Impact of acyclovir use on survival of patients with ventilator-associated pneumonia and high load herpes simplex virus replication.Critical care (London, England) · 2020
    Article
12. Cytomegalovirus: A Troll in the ICU? Overview of the Literature and Perspectives for the Future.Frontiers in medicine · 2020
    Article
13. Influenza Infections and Emergent Viral Infections in Intensive Care Unit.Seminars in respiratory and critical care medicine · 2019
    Review
14. Annals of burns and fire disasters · 2017
    Article
15. Cytomegalovirus infection in immunocompetent critically ill adults: literature review.Annals of intensive care · 2016
    Review
16. Cytomegalovirus reactivation and mortality in patients with acute respiratory distress syndrome.Intensive care medicine · 2016
    Article
17. Interferon-γ production by CMV-specific CD8+ T lymphocytes provides protection against cytomegalovirus reactivation in critically ill patients.Intensive care medicine · 2016
    Observational
18. Cytomegalovirus reactivation in ICU patients.Intensive care medicine · 2016
    Article

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

3 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as