ArticlePloS one2014
Peri-operative morbidity associated with radical cystectomy in a multicenter database of community and academic hospitals.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed, 3 syntheses or guidelines pooled it, 107 citations in OpenAlex.
- Timing of symptomatic venous thromboembolism after surgery: meta-analysis.The British journal of surgery · 2023Pooled it
- The impact of preoperative nutritional status on post-surgical complication and mortality rates in patients undergoing radical cystectomy for bladder cancer: a systematic review of the literature.World journal of urology · 2021Pooled it
- The prognostic significance of preoperative serum albumin in urothelial carcinoma: a systematic review and meta-analysis.Bioscience reports · 2018Pooled it
- Perioperative Antibiotic Prophylaxis Duration in Patients Undergoing Cystectomy With Urinary Diversion: A Randomized Clinical Trial.JAMA network open · 2024Trial
- The effect of goal-directed hemodynamic therapy on clinical outcomes in patients undergoing radical cystectomy: a randomized controlled trial.BMC anesthesiology · 2023Trial
- Trial
- Optimizing local control in the surgical management of bladder cancer.Nature reviews. Urology · 2026Review
- Comparison of 90-day morbidity and mortality between ileal conduit and orthotopic neobladder following radical cystectomy in a large, multi-institutional database The Canadian CBCis experience.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2026Article
- Testosterone replacement therapy and bladder cancer.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2025Review
- Perioperative outcomes in male patients undergoing cystectomy, radical colorectal procedure or total pelvic exenteration.Translational andrology and urology · 2023Article
- Article
- Radical cystectomy, bilateral lymphadenectomy and native ureteral ligation in a patient with history of kidney transplantation.Journal of surgical case reports · 2022Article
- Comorbidity Scores and Machine Learning Methods Can Improve Risk Assessment in Radical Cystectomy for Bladder Cancer.Bladder cancer (Amsterdam, Netherlands) · 2022Article
- Can we lower the rates of cystectomy complications by modifying risk factors? A review of the literature.Central European journal of urology · 2022Review
- The learning curve for robot-assisted radical cystectomy with total intracorporeal urinary diversion based on radical cystectomy pentafecta.Frontiers in oncology · 2022Article
- Association between radical cystectomy prophylactic antimicrobial regimen and postoperative infection.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2021Article
- Validation of a German translation of the CARE questionnaire and its implementation as electronic PROM to assess patient-reported postoperative convalescence and recovery after major urological surgery.World journal of urology · 2021Article
- The natural course of urinalysis after urinary diversion.World journal of urology · 2021Article
- Randomized Controlled Trial of Laparoscopic versus Open Radical Cystectomy in a Laparoscopic Naïve Center.Advances in urology · 2021Article
- The PTWorld journal of urology · 2020Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo characterize the frequency and timing of complications following radical cystectomy in a cohort of patients treated at community and academic hospitals. PATIENTS AND
methodsRadical cystectomy patients captured from NSQIP hospitals from January 1 2006 to December 31 2012 were included. Baseline information and complications were abstracted by study surgical clinical reviewers through a validated process of medical record review and direct patient contact. We determined the incidence and timing of each complication and calculated their associations with patient and operative characteristics.
results2303 radical cystectomy patients met inclusion criteria. 1115 (48%) patients were over 70 years old and 1819 (79%) were male. Median hospital stay was 8 days (IQR 7-13 days). 1273 (55.3%) patients experienced at least 1 post-operative complication of which 191 (15.6%) occurred after hospital discharge. The most common complication was blood transfusion (n = 875; 38.0%), followed by infectious complications with 218 (9.5%) urinary tract infections, 193 (8.4%) surgical site infections, and 223 (9.7%) sepsis events. 73 (3.2%) patients had fascial dehiscence, 82 (4.0%) developed a deep vein thrombosis, and 67 (2.9%) died. Factors independently associated with the occurrence of any post-operative complication included: age, female gender, ASA class, pre-operative sepsis, COPD, low serum albumin concentration, pre-operative radiotherapy, pre-operative transfusion >4 units, and operative time >6 hours (all p<0.05).
conclusionComplications remain common following radical cystectomy and a considerable proportion occur after discharge from hospital. This study identifies risk factors for complications and quality improvement needs.
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