Evidence map›Paper›PMID 25360686›Full record

ArticlePloS one2014

Standardized full-field electroretinography in the Green Monkey (Chlorocebus sabaeus).

Joseph Bouskila, Pasha Javadi, Roberta M Palmour, Jean-François Bouchard, Maurice Ptito

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
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  4. Single opsin driven white noise ERGs in mice.Frontiers in neuroscience · 2023
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  10. Advanced Retinal Imaging and Ocular Parameters of the Rhesus Macaque Eye.Translational vision science & technology · 2021
    Article
  11. Article
  12. Functional optical coherence tomography enablesBiomedical optics express · 2020
    Article
  13. ISCEV extended protocol for the stimulus-response series for light-adapted full-field ERG.Documenta ophthalmologica. Advances in ophthalmology · 2019
    Article
  14. Article
  15. Test-retest reliability of scotopic full-field electroretinograms in rabbits.Documenta ophthalmologica. Advances in ophthalmology · 2017
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Joseph BouskilaSchool of Optometry, University of Montreal, Montreal, Quebec, Canada; Biomedical Sciences, Faculty of Medicine, University of Montreal, Montreal, Quebec, Canada.
Pasha JavadiSchool of Optometry, University of Montreal, Montreal, Quebec, Canada.
Roberta M PalmourBehavioral Science Foundation, Basseterre, St. Kitts, West Indies; Departments of Psychiatry and Human Genetics, McGill University, Montreal, Quebec, Canada.
Jean-François BouchardSchool of Optometry, University of Montreal, Montreal, Quebec, Canada.
Maurice PtitoSchool of Optometry, University of Montreal, Montreal, Quebec, Canada; BRAINlab and Neuropsychiatry Laboratory, Department of Neuroscience and Pharmacology, University of Copenhagen, Copenhagen, Denmark.
Université de Montréal · CAMcGill University · CAUniversity of Copenhagen · DK

Funding

Canadian Institutes of Health Research MOP-130337
6 · The paper itself

Abstract

Full-field electroretinography is an objective measure of retinal function, serving as an important diagnostic clinical tool in ophthalmology for evaluating the integrity of the retina. Given the similarity between the anatomy and physiology of the human and Green Monkey eyes, this species has increasingly become a favorable non-human primate model for assessing ocular defects in humans. To test this model, we obtained full-field electroretinographic recordings (ERG) and normal values for standard responses required by the International Society for Clinical Electrophysiology of Vision (ISCEV). Photopic and scotopic ERG recordings were obtained by full-field stimulation over a range of 6 log units of intensity in dark-adapted or light-adapted eyes of adult Green Monkeys (Chlorocebus sabaeus). Intensity, duration, and interval of light stimuli were varied separately. Reproducible values of amplitude and latency were obtained for the a- and b-waves, under well-controlled adaptation and stimulus conditions; the i-wave was also easily identifiable and separated from the a-b-wave complex in the photopic ERG. The recordings obtained in the healthy Green Monkey matched very well with those in humans and other non-human primate species (Macaca mulatta and Macaca fascicularis). These results validate the Green Monkey as an excellent non-human primate model, with potential to serve for testing retinal function following various manipulations such as visual deprivation or drug evaluation.

Indexed as

AnimalsChlorocebus aethiopsColor VisionDark AdaptationElectroretinographyFemaleMaleNight VisionPhotic StimulationReference StandardsTime FactorsVisual Fields

Identifiers

PMID25360686
PMCPMC4216091
OpenAlexW2108978224

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.