Evidence map›Paper›PMID 25360551›Full record

ArticlePloS one2014

Missed opportunities for early access to care of HIV-infected infants in Burkina Faso.

Malik Coulibaly, Nicolas Meda, Caroline Yonaba, Sylvie Ouedraogo, Malika Congo, Mamoudou Barry, Elisabeth Thio, Issa Siribié, Fla Koueta, Diarra Ye and 5 more

Abstract read
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Malik CoulibalyProjet MONOD ANRS 12206, Centre de Recherche Internationale pour la Santé, Site ANRS Burkina, Université de Ouagadougou, Ouagadougou, Burkina Faso.
Nicolas MedaProjet MONOD ANRS 12206, Centre de Recherche Internationale pour la Santé, Site ANRS Burkina, Université de Ouagadougou, Ouagadougou, Burkina Faso; Centre Muraz, Bobo Dioulasso, Burkina Faso.
Caroline YonabaService de Pédiatrie, CHU Yalgado Ouédraogo, Ouagadougou, Burkina Faso.
Sylvie OuedraogoService de Pédiatrie Médicale, CHU Charles de Gaulle, Ouagadougou, Burkina Faso.
Malika CongoLaboratoire de Bactériologie - Virologie CHU Yalgado Ouédraogo, Ouagadougou, Burkina Faso.
Mamoudou BarryService de laboratoire, CHU Charles de Gaulle, Ouagadougou, Burkina Faso.
Elisabeth ThioProjet MONOD ANRS 12206, Centre de Recherche Internationale pour la Santé, Site ANRS Burkina, Université de Ouagadougou, Ouagadougou, Burkina Faso.
Issa SiribiéProjet MONOD ANRS 12206, Centre de Recherche Internationale pour la Santé, Site ANRS Burkina, Université de Ouagadougou, Ouagadougou, Burkina Faso.
Fla KouetaService de Pédiatrie Médicale, CHU Charles de Gaulle, Ouagadougou, Burkina Faso.
Diarra YeService de Pédiatrie Médicale, CHU Charles de Gaulle, Ouagadougou, Burkina Faso.
Ludovic KamService de Pédiatrie, CHU Yalgado Ouédraogo, Ouagadougou, Burkina Faso.
Stéphane BlancheGroupe hospitalier Necker- Enfants malades, Paris, France.
Phillipe Van De PerreInserm U1058, Université Montpellier 1, Montpellier, France.
Valériane LeroyInserm, U897, Institut de Santé Publique, Epidémiologie et Développement (ISPED), Université de Bordeaux, Bordeaux, France.
MONOD Study Group ANRS 12206

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe World Health Organization (WHO) has recommended a universal antiretroviral therapy (ART) for all HIV-infected children before the age of two since 2010, but this implies an early identification of these infants. We described the Prevention of Mother-to-Child HIV Transmission (PMTCT) cascade, the staffing and the quality of infrastructures in pediatric HIV care facilities, in Ouagadougou, Burkina Faso.

methodsWe conducted a cross-sectional survey in 2011 in all health care facilities involved in PMTCT and pediatric HIV care in Ouagadougou. We assessed them according to their coverage in pediatric HIV care and WHO standards, through a desk review of medical registers and a semi-structured questionnaire administered to health-care workers (HCW).

resultsIn 2011, there was no offer of care in primary health care facilities for HIV-infected children in Ouagadougou. Six district hospitals and two university hospitals provided pediatric HIV care. Among the 67 592 pregnant women attending antenatal clinics in 2011, 85.9% were tested for HIV. The prevalence of HIV was 1.8% (95% Confidence Interval: 1.7%-1.9%). Among the 1 064 HIV-infected pregnant women attending antenatal clinics, 41.4% received a mother-to-child HIV transmission prevention intervention. Among the HIV-exposed infants, 313 (29.4%) had an early infant HIV test, and 306 (97.8%) of these infants tested received their result within a four-month period. Among the 40 children initially tested HIV-infected, 33 (82.5%) were referred to a health care facility, 3 (9.0%) were false positive, and 27 (90.0%) were initiated on ART. Although health care facilities were adequately supplied with HIV drugs, they were hindered by operational challenges such as shortage of infrastructures, laboratory reagents, and trained HCW.

conclusionsThe PMTCT cascade revealed bottle necks in PMTCT intervention and HIV early infant diagnosis. The staffing in HIV care and quality of health care infrastructures were also insufficient in 2011 in Ouagadougou.

Indexed as

AdolescentAnti-HIV AgentsBurkina FasoChildChild, PreschoolFemaleHealth Services AccessibilityHIV InfectionsHumansInfantInfectious Disease Transmission, VerticalMalePregnancyPregnancy Complications, InfectiousAnti-HIV Agents

Identifiers

PMID25360551
PMCPMC4215985

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.