ArticlePloS one2014
Epidemiology of hepatitis E virus in China: results from the Third National Viral Hepatitis Prevalence Survey, 2005-2006.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 57 citations in OpenAlex.
- Immunogenicity and safety of HepE Hecolin® in chronic hepatitis B patients at clinically stable stage: An open-label study in China.Human vaccines & immunotherapeutics · 2025Article
- Trends and projections of hepatitis E incidence in Jiangsu Province of eastern China from 2007 to 2021: An analysis based on age-period-cohort models.Infectious Disease Modelling · 2025Article
- Epidemiological and clinical impact of hepatitis E virus coinfection in chronic hepatitis B infected patients in Hebei, China.Frontiers in microbiology · 2025Article
- Viral hepatitis in China during 2002-2021: epidemiology and influence factors through a country-level modeling study.BMC public health · 2024Article
- Development and Application of a Nanobody-Based Competitive ELISA for Detecting Antibodies against Hepatitis E Virus from Humans and Domestic Animals.Microbiology spectrum · 2023Article
- Periodic Characteristics of Hepatitis Virus Infections From 2013 to 2020 and Their Association With Meteorological Factors in Guangdong, China: Surveillance Study.JMIR public health and surveillance · 2023Article
- Prevalence of Hepatitis E Virus (HEV) in Feral and Farmed Wild Boars in Xinjiang, Northwest China.Viruses · 2022Article
- [Consensus on prevention and treatment of hepatitis E].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2022Article
- HEV prevalence and potential risk factors in a large multi-ethnic youth cohort in China.Virology journal · 2021Article
- Hepatitis E in 24 Chinese Cities, 2008-2018: A New Analysis Method for the Disease's Occupational Characteristics.Frontiers in public health · 2021Article
- Hepatitis E Virus Seroprevalence and Associated Risk Factors in Apparently Healthy Individuals from Osun State, Nigeria.Pathogens (Basel, Switzerland) · 2020Article
- Liver diseases in the Asia-Pacific region: a Lancet Gastroenterology & Hepatology Commission.The lancet. Gastroenterology & hepatology · 2020Review
- Waterborne & foodborne viral hepatitis: A public health perspective.The Indian journal of medical research · 2019Article
- Superinfective Hepatitis E Virus Infection Aggravates Hepatocytes Injury in Chronic Hepatitis B.Current medical science · 2019Article
- Acute sporadic hepatitis E in the Zhejiang coastal area of China: a 14-year hospital-based surveillance study.Virology journal · 2019Article
- Hiding in Plain Sight? It's Time to Investigate Other Possible Transmission Routes for Hepatitis E Virus (HEV) in Developed Countries.Food and environmental virology · 2018Review
- Spatio-Temporal Epidemiology of Viral Hepatitis in China (2003-2015): Implications for Prevention and Control Policies.International journal of environmental research and public health · 2018Article
- Comparison of hepatitis E virus seroprevalence between HBsAg-positive population and healthy controls in Shandong province, China.BMC infectious diseases · 2018Article
- Health economic evaluation of immunization strategies of hepatitis E vaccine for elderly population.Human vaccines & immunotherapeutics · 2017Article
- Disease burden of hepatitis E in a rural population in China: a community-based survey.Epidemiology and infection · 2017Article
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Authors and funding
14 authors at 3 institutions in 2 countries.
Funding
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Abstract
In China, hepatitis E virus (HEV) is prevalent and causes disease, but its epidemiological profile is not well understood. We used a commercial enzyme-linked immunosorbent assay to detect total antibodies to hepatitis E virus in 15,862 serum samples collected during the Third National Viral Hepatitis Prevalence Survey. The results were analyzed to calculate estimates of HEV seroprevalence and to examine the effects of some putative risk factors. The seroprevalence of HEV in the general Chinese population during the period from 2005 through 2006 was 23.46% (95% confidence interval [CI], 18.41%-28.50%). The farming population, the age group of 15-60 year olds, and those living in the Midwest or Mideast region and in Xinjiang province had the highest seroprevalence estimates. The prevalence of HEV is high in China. The seroprevalence rate of HEV shows an unbalanced distribution among areas with different geographic location and economic development levels. The characteristics of the distribution associated may be due to the route of HEV transmission (via contaminated water or animal reservoirs). Within the same region, the seroprevalence of HEV is generally increased with age.
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