Heart failure with preserved ejection fraction - unwinding the diagnosis mystique.

Muhammad Asrar Ul Haq, Vivek Mutha, Nima Rudd, David L Hare, Chiew Wong

Abstract readReview

In one paragraph

Review in American journal of cardiovascular disease, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it

0cells of the map it votes in

9citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

Spectrum of cardiac manifestations and its relationship to outcomes in patients admitted with scrub typhus infection.World journal of critical care medicine · 2018
Article
Shortness of breath in clinical practice: A case for left atrial function and exercise stress testing for a comprehensive diastolic heart failure workup.World journal of methodology · 2017
Review
Increases of desmin and α-actinin in mouse cardiac myofibrils as a response to diastolic dysfunction.Journal of molecular and cellular cardiology · 2016
Article
Sickle cell anemia mice develop a unique cardiomyopathy with restrictive physiology.Proceedings of the National Academy of Sciences of the United States of America · 2016
Article
Cardiovascular function, compliance, and connective tissue remodeling in the turtle, Trachemys scripta, following thermal acclimation.American journal of physiology. Regulatory, integrative and comparative physiology · 2016
Article
Assessing the Value of BMI and Aerobic Capacity as Surrogate Markers for the Severity of Left Ventricular Diastolic Dysfunction in Patients with Type 2 Diabetes Who Are Obese.Clinical Medicine Insights. Cardiology · 2016
Article
Heart Failure with Preserved Ejection Fraction - Concept, Pathophysiology, Diagnosis and Challenges for Treatment.Open access Macedonian journal of medical sciences · 2015
Review
Clinical utility of exercise training in heart failure with reduced and preserved ejection fraction.Clinical Medicine Insights. Cardiology · 2015
Review
Abnormal calcium homeostasis in heart failure with preserved ejection fraction is related to both reduced contractile function and incomplete relaxation: an electromechanically detailed biophysical modeling study.Frontiers in physiology · 2015
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Muhammad Asrar Ul HaqDepartment of Cardiology, The Northern Hospital Melbourne, Australia ; Austin Health Melbourne, Australia ; Department of Medicine, University of Melbourne Australia.

Vivek MuthaDepartment of Cardiology, The Northern Hospital Melbourne, Australia ; Department of Medicine, University of Melbourne Australia.

Nima RuddDepartment of Cardiology, The Northern Hospital Melbourne, Australia ; Department of Medicine, University of Melbourne Australia.

David L HareAustin Health Melbourne, Australia ; Department of Medicine, University of Melbourne Australia.

Chiew WongDepartment of Cardiology, The Northern Hospital Melbourne, Australia ; Department of Medicine, University of Melbourne Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A precise diagnosis of diastolic dysfunction is often difficult and requires invasive techniques to determine left ventricular volume, relaxation, and compliance properties. At this current point of time there is no single non-invasive index available to adequately reflect diastolic function, perhaps because of the numerous factors that can alter diastolic function. In most clinical settings, diastolic function is estimated using Doppler echocardiography. Cardiac magnetic resonance imaging (CMRI) is yet another emerging modality for diastolic function analysis. Here we present a comprehensive review of the various parameters used to assess diastolic function as part of diagnosis of clinical syndrome "Heart failure with preserved ejection fraction (HFPEF)".

Indexed as

Diastolic dysfunctionechocardiographyHFNEFHFPEF

Identifiers

PMID25360388

PMCPMC4212885

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.