ArticleBiomedical optics express2014
Estimate of tissue composition in malignant and benign breast lesions by time-domain optical mammography.
Article in Biomedical optics express, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04767659 (Optical Monitoring of Neoadjuvant Chemotherapy and Prediction of Pathological Complete Response in Breast Cancer Patients), which is not on this map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Optical Monitoring of Neoadjuvant Chemotherapy and Prediction of Pathological Complete Response in Breast Cancer Patients
Who cites it
28 citing papers in PubMed.
- AI-assisted diffuse correlation tomography for identifying breast cancer.Journal of biomedical optics · 2025Article
- Innovative Discrete Multi-Wavelength Near-Infrared Spectroscopic (DMW-NIRS) Imaging for Rapid Breast Lesion Differentiation: Feasibility Study.Diagnostics (Basel, Switzerland) · 2025Article
- Diffuse correlation tomography: a technique to characterize tissue blood flow abnormalities in benign and malignant breast lesions.Biomedical optics express · 2024Article
- Monitoring of neoadjuvant chemotherapy through time domain diffuse optics: breast tissue composition changes and collagen discriminative potential.Biomedical optics express · 2024Article
- Investigating the feasibility of a hand-held photoacoustic imaging probe for margin assessment during breast conserving surgery.Photoacoustics · 2022Article
- Anthropomorphic Polydimethylsiloxane silicone-based phantom for Diffuse Optical Imaging.Heliyon · 2022Article
- Evaluation of a pipeline for simulation, reconstruction, and classification in ultrasound-aided diffuse optical tomography of breast tumors.Journal of biomedical optics · 2022Article
- Machine learning model with physical constraints for diffuse optical tomography.Biomedical optics express · 2021Article
- Enhanced diffuse optical tomographic reconstruction using concurrent ultrasound information.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2021Article
- Three-compartment-breast (3CB) prior-guided diffuse optical tomography based on dual-energy digital breast tomosynthesis (DBT).Biomedical optics express · 2021Article
- Multi-Wavelength Photo-Magnetic Imaging System for Photothermal Therapy Guidance.Lasers in surgery and medicine · 2021Article
- Broadband diffuse optical spectroscopy of absolute methemoglobin concentration can distinguish benign and malignant breast lesions.Journal of biomedical optics · 2021Article
- Breast cancer differential diagnosis using diffuse optical spectroscopic imaging and regression with z-score normalized data.Journal of biomedical optics · 2021Article
- Article
- Instrumental, optical and geometrical parameters affecting time-gated diffuse optical measurements: a systematic study.Biomedical optics express · 2018Article
- Development and clinical translation of photoacoustic mammography.Biomedical engineering letters · 2018Review
- High throughput detection chain for time domain optical mammography.Biomedical optics express · 2018Article
- An Automated Preprocessing Method for Diffuse Optical Tomography to Improve Breast Cancer Diagnosis.Technology in cancer research & treatment · 2018Article
- Performance assessment of diffuse optical spectroscopic imaging instruments in a 2-year multicenter breast cancer trialJournal of biomedical optics · 2017Article
- Diffuse optical tomography using semiautomated coregistered ultrasound measurements.Journal of biomedical optics · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The optical characterization of malignant and benign breast lesions is presented. Time-resolved transmittance measurements were performed in the 630-1060 nm range by means of a 7-wavelength optical mammograph, providing both imaging and spectroscopy information. A total of 62 lesions were analyzed, including 33 malignant and 29 benign lesions. The characterization of breast lesions was performed applying a perturbation model based on the high-order calculation of the pathlength of photons inside the lesion, which led to the assessment of oxy- and deoxy-hemoglobin, lipids, water and collagen concentrations. Significant variations between tumor and healthy tissue were observed in terms of both absorption properties and constituents concentration. In particular, benign lesions and tumors show a statistically significant discrimination in terms of absorption at several wavelengths and also in terms of oxy-hemoglobin and collagen content.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.