ArticleBiomedical optics express2014
OCT 3-D surface topography of isolated human crystalline lenses.
Article in Biomedical optics express, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
20 citing papers in PubMed, 38 citations in OpenAlex.
- Crystalline lens geometry from a clinical OCT-based biometer in pre-cataract surgery patients.Research square · 2026Article
- A Novel Method for Analysing the Curvature of the Anterior Lens: Multi-Radial Scheimpflug Imaging and Custom Conic Fitting Algorithm.Journal of imaging · 2025Article
- Age-Related Changes in Lens Elasticity Contribute More to Accommodative Decline Than Shape Change.Investigative ophthalmology & visual science · 2025Article
- Intraoperative quantitative crystalline lens nuclear opacities analysis based on crystalline lenSx platform.BMC ophthalmology · 2024Article
- Estimation of the full shape of the crystalline lens from OCT: validation using stretched donor lenses.Biomedical optics express · 2023Article
- Forensic comparison of fired cartridge cases: Feature-extraction methods for feature-based calculation of likelihood ratios.Forensic science international. Synergy · 2022Article
- Increased crystalline lens coverage in optical coherence tomography with oblique scanning and volume stitching.Biomedical optics express · 2021Article
- Lens Biometry in Congenital Lens Deformities: A Swept-Source Anterior Segment OCT Analysis.Frontiers in medicine · 2021Article
- In vivo SS-OCT imaging of crystalline lens sutures.Biomedical optics express · 2020Article
- Age-Related Changes to the Three-Dimensional Full Shape of the Isolated Human Crystalline Lens.Investigative ophthalmology & visual science · 2020Article
- Association between axial length and in vivo human crystalline lens biometry during accommodation: a swept-source optical coherence tomography study.Japanese journal of ophthalmology · 2020Article
- System for on- and off-axis volumetric OCT imaging and ray tracing aberrometry of the crystalline lens.Biomedical optics express · 2018Article
- Volumetric macro- and micro-scale assessment of crystalline lens opacities in cataract patients using long-depth-range swept source optical coherence tomography.Biomedical optics express · 2018Article
- Peripheral Defocus of the Monkey Crystalline Lens With Accommodation in a Lens Stretcher.Investigative ophthalmology & visual science · 2018Article
- Three-dimensional OCT based guinea pig eye model: relating morphology and optics.Biomedical optics express · 2017Article
- In vivo crystalline lens measurements with novel swept-source optical coherent tomography: an investigation on variability of measurement.BMJ open ophthalmology · 2017Article
- Full 3-D OCT-based pseudophakic custom computer eye model.Biomedical optics express · 2016Article
- OCT-based crystalline lens topography in accommodating eyes.Biomedical optics express · 2015Article
- Measurement of Crystalline Lens Volume During Accommodation in a Lens Stretcher.Investigative ophthalmology & visual science · 2015Article
- Changes in monkey crystalline lens spherical aberration during simulated accommodation in a lens stretcher.Investigative ophthalmology & visual science · 2015Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
Quantitative 3-D Optical Coherence Tomography was used to measure surface topography of 36 isolated human lenses, and to evaluate the relationship between anterior and posterior lens surface shape and their changes with age. All lens surfaces were fitted to 6th order Zernike polynomials. Astigmatism was the predominant surface aberration in anterior and posterior lens surfaces (accounting for ~55% and ~63% of the variance respectively), followed by spherical terms, coma, trefoil and tetrafoil. The amount of anterior and posterior surface astigmatism did not vary significantly with age. The relative angle between anterior and posterior surface astigmatism axes was on average 36.5 deg, tended to decrease with age, and was >45 deg in 36.1% lenses. The anterior surface RMS spherical term, RMS coma and 3rd order RMS decreased significantly with age. In general, there was a statistically significant correlation between the 3rd and 4th order terms of the anterior and posterior surfaces. Understanding the coordination of anterior and posterior lens surface geometries and their topographical changes with age sheds light into the role of the lens in the optical properties of the eye and the lens aging mechanism.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.