Evidence map›Paper›PMID 25360356›Full record

ArticleBiomedical optics express2014

Remote focal scanning optical projection tomography with an electrically tunable lens.

Lingling Chen, Sunil Kumar, Douglas Kelly, Natalie Andrews, Margaret J Dallman, Paul M W French, James McGinty

Abstract read
In one paragraph

Article in Biomedical optics express, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Optical projection tomography implemented for accessibility and low cost (Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2024
    Article
  2. Article
  3. Recent advances in oblique plane microscopy.Nanophotonics (Berlin, Germany) · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lingling ChenPhotonics Group, Department of Physics, Imperial College London, SW7 2AZ, UK.
Sunil KumarPhotonics Group, Department of Physics, Imperial College London, SW7 2AZ, UK.
Douglas KellyInstitute for Chemical Biology, Department of Chemistry, Imperial College London, SW7 2AZ, UK.
Natalie AndrewsInstitute for Chemical Biology, Department of Chemistry, Imperial College London, SW7 2AZ, UK.
Margaret J DallmanDivision of Cell and Molecular Biology, Department of Life Sciences, Imperial College London, SW7 2AZ, UK ; Centre for Integrative Systems Biology, Department of Life Sciences, Imperial College London, SW7 2AZ, UK.
Paul M W FrenchPhotonics Group, Department of Physics, Imperial College London, SW7 2AZ, UK.
James McGintyPhotonics Group, Department of Physics, Imperial College London, SW7 2AZ, UK.

Funding

Medical Research Council MR/K011561/1
6 · The paper itself

Abstract

We describe a remote focal scanning technique for optical projection tomography (OPT) implemented with an electrically tunable lens (ETL) that removes the need to scan the specimen or objective lens. Using a 4× objective lens the average spatial resolution is improved by ∼46% and the light collection efficiency by a factor of ∼6.76, thereby enabling increased acquisition speed and reduced light dose. This convenient implementation is particularly appropriate for lower magnifications and larger sample diameters where axial objective scanning would encounter problems with speed and stability.

Indexed as

(170.6900) Three-dimensional microscopy(170.6960) Tomography

Identifiers

PMID25360356
PMCPMC4206308

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.