ArticleGeriatric orthopaedic surgery & rehabilitation2014
The use of computed tomography attenuation to evaluate osteoporosis following acute fractures of the thoracic and lumbar vertebra.
Article in Geriatric orthopaedic surgery & rehabilitation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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25 citing papers in PubMed, 50 citations in OpenAlex.
- Screening performance of sternal CT attenuation for opportunistic osteoporosis.BMC musculoskeletal disorders · 2026Article
- Risk factors for immediate severe pain in patients with thoracolumbar junction fracture treated with percutaneous pedicle screw fixation: a retrospective study of 598 patients.Journal of orthopaedic surgery and research · 2026Article
- Severe Disc degeneration is associated with lower caudal subendplate hounsfield unit values in degenerative lumbar spinal stenosis.BMC musculoskeletal disorders · 2026Article
- Low energy Schatzker IV, V, and VI tibial plateau fractures are a marker of local poor bone quality.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026Article
- Evaluating Bone Mass with Opportunistic Chest CT: T8 as the Optimal Vertebral Level.Calcified tissue international · 2025Article
- A Novel Approach by Integrating CT-Based Imaging Data and Machine Learning to Predict Patient-Specific Young's Modulus Values.Advances in orthopedics · 2025Article
- Potential Predictive of Thoracic CT Value and Bone Mineral Density T-Value in COPD Complicated with Osteoporosis.International journal of general medicine · 2024Article
- Factors influencing vertebral collapse in osteoporotic vertebral fractures: a case-control study of symptomatic patients attended in the emergency department.Archives of osteoporosis · 2023Article
- Artificial Intelligence Applications for Osteoporosis Classification Using Computed Tomography.Bioengineering (Basel, Switzerland) · 2023Review
- Correlation analysis of the vertebral compression degree and CT HU value in elderly patients with osteoporotic thoracolumbar fractures.Journal of orthopaedic surgery and research · 2023Review
- Perioperative morbidity and mortality in octogenarians sustaining traumatic osteoporotic type 4 and 5 thoracolumbar and lumbar fractures: a retrospective study with 3 years follow-up.Acta neurochirurgica · 2023Article
- Diagnosis of Osteoporosis by Quantifying Volumetric Bone Mineral Density of Lumbar Vertebrae Using Abdominal CT Images and Two-Compartment Model.Healthcare (Basel, Switzerland) · 2023Article
- Opportunistic Screening Techniques for Analysis of CT Scans.Current osteoporosis reports · 2023Review
- Bone Mineral Density Prediction from CT Image: A Novel Approach using ANN.Applied bionics and biomechanics · 2023Article
- Application of Deep Convolutional Neural Networks in the Diagnosis of Osteoporosis.Sensors (Basel, Switzerland) · 2022Article
- Comparison of the Classification Results Accuracy for CT Soft Tissue and Bone Reconstructions in Detecting the Porosity of a Spongy Tissue.Journal of clinical medicine · 2022Article
- Impact of Sarcopenia and Bone Mineral Density on Implant Failure after Dorsal Instrumentation in Patients with Osteoporotic Vertebral Fractures.Medicina (Kaunas, Lithuania) · 2022Article
- Opportunistic CT screening predicts individuals at risk of major osteoporotic fracture.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021Article
- Characteristics of vertebral CT Hounsfield units in elderly patients with acute vertebral fragility fractures.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2020Article
- CT Derived Hounsfield Unit: An Easy Way to Determine Osteoporosis and Radiation Related Fracture Risk in Irradiated Patients.Frontiers in oncology · 2020Article
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRelatively few patients have dual-energy x-ray absorptiometry to quantify the magnitude of bone loss as they age. Recent work correlates mean computed tomography (CT) attenuation in the level I (L1) vertebra with bone mineral density (BMD), making it possible to objectively evaluate the magnitude of bone loss in osteoporosis by this method. The aims of this study were to evaluate the utility of using CT scans in patients with acute thoracic and lumbar spine fractures to diagnose osteoporosis and using CT attenuation to evaluate the association between age and BMD.
methodsWe performed a retrospective study of patients with acute fractures of the thoracic or lumbar spine who had also undergone an abdominal (or L1) CT scan and compared mean CT attenuation in L1 against threshold values. We also compared differences in CT attenuation between younger (<65 years) and older (≥65 years) and older patients.
resultsA total of 124 patients were evaluated (74 thoracic and 50 lumbar fractures). Overall, there was a strong correlation between age and bone density as measured by CT attenuation (r = -.76). Among those with thoracic fractures (<65 years), mean CT attenuation was 196.51 HU. Forty-one patients were ≥65 years and had mean CT attenuation of 105.90 HU (P < .001). In patients with lumbar fractures, 27 patients were <65 years and had a mean CT attenuation of 192.26 HU and 23 patients were ≥65 years and had mean CT attenuation of 114.31 HU (P < .001). At the threshold of 110 HU, set for specificity, the magnitude of difference between the age-stratified cohorts was greater in the thoracic spine (P < .0001 vs P = .003). DISCUSSION: Using opportunistic CT, we demonstrate the relative frequency of osteoporosis in patients with acute fractures of the thoracic and lumbar spine and confirm that the association increases with age. The CT attenuation may provide a cheap and convenient method to help confirm a clinical diagnosis of osteoporosis in patients with fractures.
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