ArticleFrontiers in plant science2014
Methanol and ethanol modulate responses to danger- and microbe-associated molecular patterns.
Article in Frontiers in plant science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 55 citations in OpenAlex.
- Pectin under stress: Pectin methylesterases at the core of cell wall remodeling, integrity sensing, and signaling in plants.Plant communications · 2026Review
- PME10 Is a Pectin Methylesterase Driving PME Activity and Immunity Against Botrytis cinerea in Grapevine (Vitis vinifera L.).Plant biotechnology journal · 2025Article
- Structure-Function Analysis of Volatile (Z)-3-Fatty Alcohols in Tomato.Journal of chemical ecology · 2025Article
- Exocyst subunits EXO70B1 and B2 contribute to stomatal dynamics and cell wall modifications.Frontiers in plant science · 2025Article
- Genomic Insights into the Landfill Microbial Community: Denitrifying Activity Supporting One-Carbon Utilization.Applied biochemistry and biotechnology · 2024Article
- Pull the fuzes: Processing protein precursors to generate apoplastic danger signals for triggering plant immunity.Plant communications · 2024Review
- Homogalacturonan Pectins Tuned as an Effect of Susceptible rbohD, Col-0-Reactions, and Resistance rbohF-, rbohD/F-Reactions to TuMV.International journal of molecular sciences · 2024Article
- Plant Cell Wall Integrity Perturbations and Priming for Defense.Plants (Basel, Switzerland) · 2022Review
- Stress-Induced Volatile Emissions and Signalling in Inter-Plant Communication.Plants (Basel, Switzerland) · 2022Review
- The Plant Invertase/Pectin Methylesterase Inhibitor Superfamily.Frontiers in plant science · 2022Review
- AtPME17 is a functional Arabidopsis thaliana pectin methylesterase regulated by its PRO region that triggers PME activity in the resistance to Botrytis cinerea.Molecular plant pathology · 2020Article
- Post-Synthetic Reduction of Pectin Methylesterification Causes Morphological Abnormalities and Alterations to Stress Response inPlants (Basel, Switzerland) · 2020Article
- Influence of cell wall polymers and their modifying enzymes during plant-aphid interactions.Journal of experimental botany · 2020Review
- Perception of Damaged Self in Plants.Plant physiology · 2020Review
- Survey of Sensitivity to Fatty Acid-Amino Acid Conjugates in the Solanaceae.Journal of chemical ecology · 2020Article
- Sweet Immunity: Inulin Boosts Resistance of Lettuce (International journal of molecular sciences · 2019Article
- Article
- Damage-Associated Molecular Pattern-Triggered Immunity in Plants.Frontiers in plant science · 2019Review
- Methanol induces cytosolic calcium variations, membrane depolarization and ethylene production in arabidopsis and tobacco.Annals of botany · 2018Article
- MAP kinases associate with high molecular weight multiprotein complexes.Journal of experimental botany · 2018Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Methanol is a byproduct of cell wall modification, released through the action of pectin methylesterases (PMEs), which demethylesterify cell wall pectins. Plant PMEs play not only a role in developmental processes but also in responses to herbivory and infection by fungal or bacterial pathogens. Molecular mechanisms that explain how methanol affects plant defenses are poorly understood. Here we show that exogenously supplied methanol alone has weak effects on defense signaling in three dicot species, however, it profoundly alters signaling responses to danger- and microbe-associated molecular patterns (DAMPs, MAMPs) such as the alarm hormone systemin, the bacterial flagellum-derived flg22 peptide, and the fungal cell wall-derived oligosaccharide chitosan. In the presence of methanol the kinetics and amplitudes of DAMP/MAMP-induced MAP kinase (MAPK) activity and oxidative burst are altered in tobacco and tomato suspension-cultured cells, in Arabidopsis seedlings and tomato leaf tissue. As a possible consequence of altered DAMP/MAMP signaling, methanol suppressed the expression of the defense genes PR-1 and PI-1 in tomato. In cell cultures of the grass tall fescue (Festuca arundinacea, Poaceae, Monocots), methanol alone activates MAPKs and increases chitosan-induced MAPK activity, and in the darnel grass Lolium temulentum (Poaceae), it alters wound-induced MAPK signaling. We propose that methanol can be recognized by plants as a sign of the damaged self. In dicots, methanol functions as a DAMP-like alarm signal with little elicitor activity on its own, whereas it appears to function as an elicitor-active DAMP in monocot grasses. Ethanol had been implicated in plant stress responses, although the source of ethanol in plants is not well established. We found that it has a similar effect as methanol on responses to MAMPs and DAMPs.
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