ArticleFrontiers in computational neuroscience2014
Systematic analysis of the contributions of stochastic voltage gated channels to neuronal noise.
Article in Frontiers in computational neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Spontaneous calcium transients in hair cell stereocilia.Scientific reports · 2025Article
- Comparative study of brain functional imaging of brain in patients with mild to moderate Alzheimer's disease based on functional near infrared spectroscopy.BMC neurology · 2025Article
- Response sub-additivity and variability quenching in visual cortex.Nature reviews. Neuroscience · 2024Review
- Power spectral analysis of voltage-gated channels in neurons.Frontiers in neuroinformatics · 2024Article
- A stochastic model of hippocampal synaptic plasticity with geometrical readout of enzyme dynamics.eLife · 2023Article
- Article
- What is the dynamical regime of cerebral cortex?Neuron · 2021Review
- Circadian Modulation of Neurons and Astrocytes Controls Synaptic Plasticity in Hippocampal Area CA1.Cell reports · 2020Article
- Conserved Expression of Nav1.7 and Nav1.8 Contribute to the Spontaneous and Thermally Evoked Excitability in IL-6 and NGF-Sensitized Adult Dorsal Root Ganglion Neurons In Vitro.Bioengineering (Basel, Switzerland) · 2020Article
- Theoretical Aspects of Resting-State Cardiomyocyte Communication for Multi-Nodal Nano-Actuator Pacemakers.Sensors (Basel, Switzerland) · 2020Article
- Psychoanalysis and Neuroscience: The Bridge Between Mind and Brain.Frontiers in psychology · 2019Article
- Sparse bursts optimize information transmission in a multiplexed neural code.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Neuroaging through the Lens of the Resting State Networks.BioMed research international · 2018Review
- Relationships between short and fast brain timescales.Cognitive neurodynamics · 2017Article
- Methodology of Recurrent Laguerre-Volterra Network for Modeling Nonlinear Dynamic Systems.IEEE transactions on neural networks and learning systems · 2017Article
- Anti-correlations in the degree distribution increase stimulus detection performance in noisy spiking neural networks.Journal of computational neuroscience · 2017Article
- A Microscopic Capacitor Model of Voltage Coupling in Membrane Proteins: Gating Charge Fluctuations in Ci-VSD.The journal of physical chemistry. B · 2016Article
- Balanced ionotropic receptor dynamics support signal estimation via voltage-dependent membrane noise.Journal of neurophysiology · 2016Article
- New Perspectives on Spontaneous Brain Activity: Dynamic Networks and Energy Matter.Frontiers in human neuroscience · 2016Review
- A temperature rise reduces trial-to-trial variability of locust auditory neuron responses.Journal of neurophysiology · 2015Article
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2 authors.
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Abstract
Electrical signaling in neurons is mediated by the opening and closing of large numbers of individual ion channels. The ion channels' state transitions are stochastic and introduce fluctuations in the macroscopic current through ion channel populations. This creates an unavoidable source of intrinsic electrical noise for the neuron, leading to fluctuations in the membrane potential and spontaneous spikes. While this effect is well known, the impact of channel noise on single neuron dynamics remains poorly understood. Most results are based on numerical simulations. There is no agreement, even in theoretical studies, on which ion channel type is the dominant noise source, nor how inclusion of additional ion channel types affects voltage noise. Here we describe a framework to calculate voltage noise directly from an arbitrary set of ion channel models, and discuss how this can be use to estimate spontaneous spike rates.
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